| Literature DB >> 16724855 |
Hiroshi Morita1, Toru Iizuka, Akira Gonda, Hideji Itokawa, Koichi Takeya.
Abstract
Two new cyclic nonapeptides, cycloleonuripeptide E, cyclo (-Ala-Pro-Ile-Val-Ala-Ala-Phe-Thr-Pro-), and cycloleonuripeptide F, cyclo (-Gly-Tyr-Pro-Leu-Pro-Phe-Tyr-Pro-Pro-), have been isolated from the fruits of Leonurus heterophyllus, and their structures were elucidated by 2D NMR analysis and chemical degradation. Cycloleonuripeptides E (1) and F (2) showed moderate vasorelaxant effects on rat aorta.Entities:
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Year: 2006 PMID： 16724855 DOI： 10.1021/np050544k
Source DB: PubMed Journal: J Nat Prod ISSN： 0163-3864 Impact factor: 4.050