BACKGROUND AND OBJECTIVES: Gallbladder cancer (GBC) is a lethal disease with a wide geographical, ethnic, and cultural variation suggesting major environmental influences such as diet and life style factors in the development of disease. An objective assessment of demographic profile and full implication of these features to recognize the population at risk is needed. This study was therefore undertaken to study the demography of GBC in Varanasi. METHODS: A retrospective study as a case-control model comprised 328 cases of GBC and 328 controls with gallstone disease (GSD). The relevant demographic data were collected and analyzed for identification of independent significant features and for the risk of GBC based on these features by calculating odds ratio. RESULTS AND CONCLUSIONS: GBC predominantly a disease of females belonged to fourth and fifth decade of life. Among 328 cases of GBC only 75 were male and 253 female (M:F = 1:3.37). Majority of GBC patients were above 40 years and multiparous females. Family history of GBC was higher in GBC patients. Majority of GBC patients were of low socioeconomic status and hailed from rural background. This group tends to consume open mustard oil and water from hand pump. This study emphasizes the usefulness of demographic evaluation in diagnosis of GBC and a systematic approach to assessment of demographic features of GBC is recommended. Copyright 2006 Wiley-Liss, Inc.
BACKGROUND AND OBJECTIVES:Gallbladder cancer (GBC) is a lethal disease with a wide geographical, ethnic, and cultural variation suggesting major environmental influences such as diet and life style factors in the development of disease. An objective assessment of demographic profile and full implication of these features to recognize the population at risk is needed. This study was therefore undertaken to study the demography of GBC in Varanasi. METHODS: A retrospective study as a case-control model comprised 328 cases of GBC and 328 controls with gallstone disease (GSD). The relevant demographic data were collected and analyzed for identification of independent significant features and for the risk of GBC based on these features by calculating odds ratio. RESULTS AND CONCLUSIONS: GBC predominantly a disease of females belonged to fourth and fifth decade of life. Among 328 cases of GBC only 75 were male and 253 female (M:F = 1:3.37). Majority of GBC patients were above 40 years and multiparous females. Family history of GBC was higher in GBC patients. Majority of GBC patients were of low socioeconomic status and hailed from rural background. This group tends to consume open mustard oil and water from hand pump. This study emphasizes the usefulness of demographic evaluation in diagnosis of GBC and a systematic approach to assessment of demographic features of GBC is recommended. Copyright 2006 Wiley-Liss, Inc.
Authors: Jean M Butte; Javiera Torres; Emanuela F Veras; Kenichi Matsuo; Mithat Gönen; Michael I D'Angelica; Enrique Waugh; Manuel Meneses; Yoshiyaki Inayama; Yuman Fong; Ronald P Dematteo; Hernan De La Fuente; Itaru Endo; David S Klimstra; William R Jarnagin Journal: Ann Surg Oncol Date: 2012-12-01 Impact factor: 5.344
Authors: Alison L Van Dyke; Margaret S Langhamer; Bin Zhu; Ruth M Pfeiffer; Demetrius Albanes; Gabriella Andreotti; Laura E Beane Freeman; Andrew T Chan; Neal D Freedman; Susan M Gapstur; Graham G Giles; Francine Grodstein; Linda M Liao; Juhua Luo; Roger L Milne; Kristine R Monroe; Marian L Neuhouser; Jenny N Poynter; Mark P Purdue; Kim Robien; Catherine Schairer; Rashmi Sinha; Stephanie Weinstein; Xuehong Zhang; Jessica L Petrick; Katherine A McGlynn; Peter T Campbell; Jill Koshiol Journal: Cancer Epidemiol Biomarkers Prev Date: 2018-01-16 Impact factor: 4.254