Literature DB >> 16724098

CEACAM1: contact-dependent control of immunity.

Scott D Gray-Owen1, Richard S Blumberg.   

Abstract

The carcinoembryonic-antigen-related cell-adhesion molecule (CEACAM) family of proteins has been implicated in various intercellular-adhesion and intracellular-signalling-mediated effects that govern the growth and differentiation of normal and cancerous cells. Recent studies show that there is an important role for members of the CEACAM family in modulating the immune responses associated with infection, inflammation and cancer. In this Review, we consider the evidence for CEACAM involvement in immunity, with a particular emphasis on CEACAM1, which functions as a regulatory co-receptor for both lymphoid and myeloid cell types.

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Year:  2006        PMID： 16724098     DOI： 10.1038/nri1864

Source DB:  PubMed          Journal:  Nat Rev Immunol        ISSN： 1474-1733            Impact factor:   53.106


  215 in total

1.  A Multikinase and DNA-PK Inhibitor Combination Immunomodulates Melanomas, Suppresses Tumor Progression, and Enhances Immunotherapies.

Authors:  Alexander K Tsai; Asra Y Khan; Christina E Worgo; Lucy L Wang; Yuanyuan Liang; Eduardo Davila
Journal:  Cancer Immunol Res       Date:  2017-08-03       Impact factor: 11.151

2.  CEACAM1 regulates TIM-3-mediated tolerance and exhaustion.

Authors:  Yu-Hwa Huang; Chen Zhu; Yasuyuki Kondo; Ana C Anderson; Amit Gandhi; Andrew Russell; Stephanie K Dougan; Britt-Sabina Petersen; Espen Melum; Thomas Pertel; Kiera L Clayton; Monika Raab; Qiang Chen; Nicole Beauchemin; Paul J Yazaki; Michal Pyzik; Mario A Ostrowski; Jonathan N Glickman; Christopher E Rudd; Hidde L Ploegh; Andre Franke; Gregory A Petsko; Vijay K Kuchroo; Richard S Blumberg
Journal:  Nature       Date:  2014-10-26       Impact factor: 49.962

3.  Tumor angiogenesis mediated by myeloid cells is negatively regulated by CEACAM1.

Authors:  Rongze Lu; Maciej Kujawski; Hao Pan; John E Shively
Journal:  Cancer Res       Date:  2012-03-09       Impact factor: 12.701

Review 4.  A bacterial siren song: intimate interactions between Neisseria and neutrophils.

Authors:  Alison K Criss; H Steven Seifert
Journal:  Nat Rev Microbiol       Date:  2012-01-31       Impact factor: 60.633

5.  Diverse oligomeric states of CEACAM IgV domains.

Authors:  Daniel A Bonsor; Sebastian Günther; Robert Beadenkopf; Dorothy Beckett; Eric J Sundberg
Journal:  Proc Natl Acad Sci U S A       Date:  2015-10-19       Impact factor: 11.205

6.  Interferon regulatory factor 1 and a variant of heterogeneous nuclear ribonucleoprotein L coordinately silence the gene for adhesion protein CEACAM1.

Authors:  Kenneth J Dery; Craig Silver; Lu Yang; John E Shively
Journal:  J Biol Chem       Date:  2018-05-02       Impact factor: 5.157

7.  The Helicobacter pylori adhesin protein HopQ exploits the dimer interface of human CEACAMs to facilitate translocation of the oncoprotein CagA.

Authors:  Daniel A Bonsor; Qing Zhao; Barbara Schmidinger; Evelyn Weiss; Jingheng Wang; Daniel Deredge; Robert Beadenkopf; Blaine Dow; Wolfgang Fischer; Dorothy Beckett; Patrick L Wintrode; Rainer Haas; Eric J Sundberg
Journal:  EMBO J       Date:  2018-05-03       Impact factor: 11.598

Review 8.  CEACAM1 and the regulation of mucosal inflammation.

Authors:  T Nagaishi; Z Chen; L Chen; H Iijima; A Nakajima; R S Blumberg
Journal:  Mucosal Immunol       Date:  2008-11       Impact factor: 7.313

Review 9.  The role of CEA-related cell adhesion molecule-1 (CEACAM1) in vascular homeostasis.

Authors:  Uwe Rueckschloss; Stefanie Kuerten; Süleyman Ergün
Journal:  Histochem Cell Biol       Date:  2016-09-30       Impact factor: 4.304

Review 10.  Recognition of additional roles for immunoglobulin domains in immune function.

Authors:  John P Cannon; Larry J Dishaw; Robert N Haire; Ronda T Litman; David A Ostrov; Gary W Litman
Journal:  Semin Immunol       Date:  2009-12-08       Impact factor: 11.130
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