OBJECTIVE: The independent risk factors for aneurysm growth were retrospectively investigated in 130 patients with unruptured aneurysms who were followed up by 0.5-T serial magnetic resonance angiography with stereoscopic images. METHODS: Age, sex, site of aneurysm, size of aneurysm, multiplicity of aneurysms, type of circle of Willis, length of follow-up period, cerebrovascular event, hypertension, diabetes, hyperlipidemia, smoking habit, and family history of subarachnoid hemorrhage were investigated using multiple logistic analysis. RESULTS: Fourteen patients (16 aneurysms) among the 130 patients (159 aneurysms) showed aneurysm growth (10.8%) during follow-up of 10 to 69 months (mean 29.3 +/- 10.5 mo). Multiple logistic analysis disclosed that location on the middle cerebral artery (odds ratio [OR] 0.08, P < 0.01), multiplicity of aneurysms (OR 68.5, P < 0.01), aneurysm size of 5 mm or larger (OR 1.17, P = 0.05), and family history of subarachnoid hemorrhage (OR 10.9, P < 0.01) were independent risk factors. CONCLUSION: Location on the middle cerebral artery, multiplicity, aneurysm size of 5 mm or larger, and family history of subarachnoid hemorrhage are independent risk factors for aneurysm growth. These results may help to determine the treatment choice for unruptured aneurysms.
OBJECTIVE: The independent risk factors for aneurysm growth were retrospectively investigated in 130 patients with unruptured aneurysms who were followed up by 0.5-T serial magnetic resonance angiography with stereoscopic images. METHODS: Age, sex, site of aneurysm, size of aneurysm, multiplicity of aneurysms, type of circle of Willis, length of follow-up period, cerebrovascular event, hypertension, diabetes, hyperlipidemia, smoking habit, and family history of subarachnoid hemorrhage were investigated using multiple logistic analysis. RESULTS: Fourteen patients (16 aneurysms) among the 130 patients (159 aneurysms) showed aneurysm growth (10.8%) during follow-up of 10 to 69 months (mean 29.3 +/- 10.5 mo). Multiple logistic analysis disclosed that location on the middle cerebral artery (odds ratio [OR] 0.08, P < 0.01), multiplicity of aneurysms (OR 68.5, P < 0.01), aneurysm size of 5 mm or larger (OR 1.17, P = 0.05), and family history of subarachnoid hemorrhage (OR 10.9, P < 0.01) were independent risk factors. CONCLUSION: Location on the middle cerebral artery, multiplicity, aneurysm size of 5 mm or larger, and family history of subarachnoid hemorrhage are independent risk factors for aneurysm growth. These results may help to determine the treatment choice for unruptured aneurysms.
Authors: Maria V Irazabal; John Huston; Vickie Kubly; Sandro Rossetti; Jamie L Sundsbak; Marie C Hogan; Peter C Harris; Robert D Brown; Vicente E Torres Journal: Clin J Am Soc Nephrol Date: 2011-05-05 Impact factor: 8.237
Authors: W Brinjikji; Y-Q Zhu; G Lanzino; H J Cloft; M H Murad; Z Wang; D F Kallmes Journal: AJNR Am J Neuroradiol Date: 2015-11-26 Impact factor: 3.825
Authors: M Hayakawa; T Tanaka; A Sadato; K Adachi; K Ito; N Hattori; T Omi; M Oheda; K Katada; K Murayama; Y Kato; Y Hirose Journal: Clin Neuroradiol Date: 2013-08-03 Impact factor: 3.649
Authors: Gabriel Rinkel; Nima Etminan; Katharina A M Hackenberg; Ale Algra; Rustam Al-Shahi Salman; Juhana Frösen; David Hasan; Seppo Juvela; David Langer; Philip Meyers; Akio Morita Journal: Neurocrit Care Date: 2019-06 Impact factor: 3.210