Literature DB >> 16722619

Medicinal chemistry of combretastatin A4: present and future directions.

Gian Cesare Tron1, Tracey Pirali, Giovanni Sorba, Francesca Pagliai, Sara Busacca, Armando A Genazzani.   

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Year:  2006        PMID： 16722619     DOI： 10.1021/jm0512903

Source DB:  PubMed          Journal:  J Med Chem        ISSN： 0022-2623            Impact factor:   7.446


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  93 in total

1.  Synthesis and evaluation of 1,5-disubstituted tetrazoles as rigid analogues of combretastatin A-4 with potent antiproliferative and antitumor activity.

Authors:  Romeo Romagnoli; Pier Giovanni Baraldi; Maria Kimatrai Salvador; Delia Preti; Mojgan Aghazadeh Tabrizi; Andrea Brancale; Xian-Hua Fu; Jun Li; Su-Zhan Zhang; Ernest Hamel; Roberta Bortolozzi; Giuseppe Basso; Giampietro Viola
Journal:  J Med Chem       Date:  2011-12-21       Impact factor: 7.446

2.  Synthesis and antitumor activity of 1,5-disubstituted 1,2,4-triazoles as cis-restricted combretastatin analogues.

Authors:  Romeo Romagnoli; Pier Giovanni Baraldi; Olga Cruz-Lopez; Carlota Lopez Cara; Maria Dora Carrion; Andrea Brancale; Ernest Hamel; Longchuan Chen; Roberta Bortolozzi; Giuseppe Basso; Giampietro Viola
Journal:  J Med Chem       Date:  2010-05-27       Impact factor: 7.446

3.  Computational Design and Synthesis of Novel Fluoro-Analogs of Combretastatins A-4 and A-1.

Authors:  Yao Zong; Christie Shea; Katherine Maffucci; Iwao Ojima
Journal:  J Fluor Chem       Date:  2017-09-10       Impact factor: 2.050

Review 4.  Antivascular actions of microtubule-binding drugs.

Authors:  Edward L Schwartz
Journal:  Clin Cancer Res       Date:  2009-04-07       Impact factor: 12.531

5.  Design, synthesis, and biological evaluations of 2,5-diaryl-2,3-dihydro-1,3,4-oxadiazoline analogs of combretastatin-A4.

Authors:  Lauren Lee; Lyda M Robb; Megan Lee; Ryan Davis; Hilary Mackay; Sameer Chavda; Balaji Babu; Erin L O'Brien; April L Risinger; Susan L Mooberry; Moses Lee
Journal:  J Med Chem       Date:  2010-01-14       Impact factor: 7.446

6.  Synthesis and antitumor molecular mechanism of agents based on amino 2-(3',4',5'-trimethoxybenzoyl)benzo[b]furan: inhibition of tubulin and induction of apoptosis.

Authors:  Romeo Romagnoli; Pier Giovanni Baraldi; Carlota Lopez-Cara; Olga Cruz-Lopez; Maria Dora Carrion; Maria Kimatrai Salvador; Jaime Bermejo; Sara Estévez; Francisco Estévez; Jan Balzarini; Andrea Brancale; Antonio Ricci; Longchuan Chen; Jae Gwan Kim; Ernest Hamel
Journal:  ChemMedChem       Date:  2011-08-01       Impact factor: 3.466

7.  Molecular modeling study, synthesis and biological evaluation of combretastatin A-4 analogues as anticancer agents and tubulin inhibitors.

Authors:  Yang Ping Quan; Li Ping Cheng; Tian Chi Wang; Wan Pang; Fan Hong Wu; Jin Wen Huang
Journal:  Medchemcomm       Date:  2017-12-06       Impact factor: 3.597

8.  Molecular docking studies, biological evaluation and synthesis of novel 3-mercapto-1,2,4-triazole derivatives.

Authors:  Javad Ghanaat; Mohammad A Khalilzadeh; Daryoush Zareyee
Journal:  Mol Divers       Date:  2020-02-17       Impact factor: 2.943

9.  Synthesis, biological evaluation and molecular docking studies of trans-indole-3-acrylamide derivatives, a new class of tubulin polymerization inhibitors.

Authors:  Sultan Nacak Baytas; Nazan Inceler; Akin Yilmaz; Abdurrahman Olgac; Sevda Menevse; Erden Banoglu; Ernest Hamel; Roberta Bortolozzi; Giampietro Viola
Journal:  Bioorg Med Chem       Date:  2014-04-20       Impact factor: 3.641

10.  New arylthioindoles and related bioisosteres at the sulfur bridging group. 4. Synthesis, tubulin polymerization, cell growth inhibition, and molecular modeling studies.

Authors:  Giuseppe La Regina; Taradas Sarkar; Ruoli Bai; Michael C Edler; Roberto Saletti; Antonio Coluccia; Francesco Piscitelli; Lara Minelli; Valerio Gatti; Carmela Mazzoccoli; Vanessa Palermo; Cristina Mazzoni; Claudio Falcone; Anna Ivana Scovassi; Vincenzo Giansanti; Pietro Campiglia; Amalia Porta; Bruno Maresca; Ernest Hamel; Andrea Brancale; Ettore Novellino; Romano Silvestri
Journal:  J Med Chem       Date:  2009-12-10       Impact factor: 7.446
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