Literature DB >> 16722000

The sensitivity of cells from normal mouse bone marrow to gamma radiation in vitro and in vivo.

E A McCulloch, J E Till.   

Abstract

1. A survival curve for the colony-forming ability of mouse bone marrow cells irradiated in vivo with Co60 gamma-rays has been obtained. The curve may be characterized by D0 of 95 rads and an extrapolation number of 1.5. 2. Comparison with the survival curve obtained for irradiated in vitro indicated a statistically significant difference in extrapolation number. Possible explanations for this finding are considered.

Entities:  

Keywords:  BONE MARROW/radiation effects; COLONY FORMING UNITS ASSAY; GAMMA RAYS

Mesh:

Year:  1962        PMID: 16722000

Source DB:  PubMed          Journal:  Radiat Res        ISSN: 0033-7587            Impact factor:   2.841


  24 in total

1.  Sensitization to radiation and alkylating agents by inhibitors of poly(ADP-ribose) polymerase is enhanced in cells deficient in DNA double-strand break repair.

Authors:  Dana A Löser; Atsushi Shibata; Akiko K Shibata; Lisa J Woodbine; Penny A Jeggo; Anthony J Chalmers
Journal:  Mol Cancer Ther       Date:  2010-06-08       Impact factor: 6.261

2.  [Collection of hematopoietic stem cells from canine peripheral blood and their ability to regenerate hematopoiesis].

Authors:  E W Herbst; T M Fliedner; W Calvo; H Schnappauf; H Meyer
Journal:  Blut       Date:  1975-06

3.  Affinity of 14C-nicotine to some cells of the lymfomyeloid system demonstrated by autoradiography.

Authors:  M Beran; P Slanina
Journal:  Experientia       Date:  1974-04-15

4.  Antiserum inactivation of hematopoietic colony forming stem cells from mice with Rauscher leukemia.

Authors:  J P Okunewick; E L Phillips; B J Brozovich
Journal:  Experientia       Date:  1974-12-15

5.  The relationship between zones of iron concentration and macroscopic surface colonies in the spleen of the mouse radiation chimera.

Authors:  D B Thomas
Journal:  J Anat       Date:  1973-01       Impact factor: 2.610

6.  Erythrocytic maturation of (Friend) virus-induced leukemic cells in spleen clones.

Authors:  G B Rossi; C Friend
Journal:  Proc Natl Acad Sci U S A       Date:  1967-10       Impact factor: 11.205

7.  Cell turnover in mammalian tissues: use of cell depletion measurements to calculate x-ray reproductive survival curves in vivo.

Authors:  T T Puck
Journal:  Proc Natl Acad Sci U S A       Date:  1965-12       Impact factor: 11.205

Review 8.  Hemopoietic precursor cell regeneration following irradiation and syngeneic marrow transplantation.

Authors:  H von Melchner
Journal:  Blut       Date:  1983-01

9.  Effects of radiation on normal tissues: hypothetical mechanisms and limitations of in situ assays of clonogenicity.

Authors:  A Michalowski
Journal:  Radiat Environ Biophys       Date:  1981       Impact factor: 1.925

10.  Sensitivity of follicular melanoblasts in newborn mouse skin to tritiated thymidine: Evidence for a long term retention of label.

Authors:  C S Potten
Journal:  Experientia       Date:  1982-12-15
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