Literature DB >> 16720795

Cognitive reserve and the relationship between depressive symptoms and awareness of deficits in dementia.

Mary Beth Spitznagel1, Geoffrey Tremont, Laura B Brown, John Gunstad.   

Abstract

Depression and low cognitive reserve are linked to impaired awareness in dementia, although their relative contributions are unknown. The authors investigated the impact of depressive symptoms and cognitive reserve on awareness in questionable and mild dementia. Sixty-six patients completed measures of cognitive reserve, awareness, and depressive symptoms. Cognitive reserve and its interaction with depressive symptoms accounted for significant proportions of variance in awareness; depressive symptoms alone did not. Depressive symptoms and awareness were positively related in high, but not low, cognitive reserve groups. Findings suggest cognitive reserve moderates the depression/awareness relationship in dementia, which may explain previously discrepant findings.

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Year:  2006        PMID： 16720795     DOI： 10.1176/jnp.2006.18.2.186

Source DB:  PubMed          Journal:  J Neuropsychiatry Clin Neurosci        ISSN： 0895-0172            Impact factor:   2.198


  9 in total

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8.  Quality of life as an outcome in Alzheimer's disease and other dementias--obstacles and goals.

Authors:  Matthias W Riepe; Thomas Mittendorf; Hans Förstl; Lutz Frölich; Martin Haupt; Reiner Leidl; Christoph Vauth; Matthias Graf von der Schulenburg
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  9 in total

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