Literature DB >> 16719834

Recent advances in clarifying prion protein functions using knockout mice and derived cell lines.

Akikazu Sakudo1, Takashi Onodera, Yoshikazu Suganuma, Takanori Kobayashi, Keiichi Saeki, Kazuyoshi Ikuta.   

Abstract

Considerable information on the functions of prion protein (PrP) has been accumulated. One experimental approach is the use of PrP gene-knockout mice and derived cell lines. This approach has contributed to elucidating the functions of cellular prion protein (PrP(C)), such as its anti-oxidative and anti-apoptotic roles. This review will introduce the recent advances in prion biology made possible by the availability of these tools.

Entities:  

Mesh：

Substances：

Year:  2006        PMID： 16719834     DOI： 10.2174/138955706776876159

Source DB:  PubMed          Journal:  Mini Rev Med Chem        ISSN： 1389-5575            Impact factor:   3.862


  11 in total

Review 1.  Redox control of prion and disease pathogenesis.

Authors:  Neena Singh; Ajay Singh; Dola Das; Maradumane L Mohan
Journal:  Antioxid Redox Signal       Date:  2010-06-01       Impact factor: 8.401

2.  Anchorless 23-230 PrPC interactomics for elucidation of PrPC protective role.

Authors:  Saima Zafar; Abdul R Asif; Sanja Ramljak; Waqas Tahir; Matthias Schmitz; Inga Zerr
Journal:  Mol Neurobiol       Date:  2014-01-05       Impact factor: 5.590

Review 3.  Role of prions in neuroprotection and neurodegeneration: a mechanism involving glutamate receptors?

Authors:  Gerald W Zamponi; Peter K Stys
Journal:  Prion       Date:  2009-10-16       Impact factor: 3.931

4.  Prion protein on astrocytes or in extracellular fluid impedes neurodegeneration induced by truncated prion protein.

Authors:  Brent Race; Kimberly Meade-White; Richard Race; Frank Baumann; Adriano Aguzzi; Bruce Chesebro
Journal:  Exp Neurol       Date:  2009-03-28       Impact factor: 5.330

5.  The prion protein knockout mouse: a phenotype under challenge.

Authors:  Andrew D Steele; Susan Lindquist; Adriano Aguzzi
Journal:  Prion       Date:  2007-04-25       Impact factor: 3.931

6.  The 5' flanking region and intron1 of the bovine prion protein gene (PRNP) are responsible for negative feedback regulation of the prion protein.

Authors:  Guangai Xue; Yoko Aida; Takashi Onodera; Akikazu Sakudo
Journal:  PLoS One       Date:  2012-03-07       Impact factor: 3.240

7.  All quiet on the neuronal front: NMDA receptor inhibition by prion protein.

Authors:  Andrew D Steele
Journal:  J Cell Biol       Date:  2008-04-28       Impact factor: 10.539

Review 8.  Prion protein (PrP) gene-knockout cell lines: insight into functions of the PrP.

Authors:  Akikazu Sakudo; Takashi Onodera
Journal:  Front Cell Dev Biol       Date:  2015-01-15

9.  Regulation of GABA(A) and glutamate receptor expression, synaptic facilitation and long-term potentiation in the hippocampus of prion mutant mice.

Authors:  Alejandra Rangel; Noelia Madroñal; Agnès Gruart; Agnès Gruart i Massó; Rosalina Gavín; Franc Llorens; Lauro Sumoy; Juan María Torres; José María Delgado-García; José Antonio Del Río
Journal:  PLoS One       Date:  2009-10-26       Impact factor: 3.240

10.  Prion protein attenuates excitotoxicity by inhibiting NMDA receptors.

Authors:  Houman Khosravani; Yunfeng Zhang; Shigeki Tsutsui; Shahid Hameed; Christophe Altier; Jawed Hamid; Lina Chen; Michelle Villemaire; Zenobia Ali; Frank R Jirik; Gerald W Zamponi
Journal:  J Cell Biol       Date:  2008-04-28       Impact factor: 10.539
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.