Iron transport in Escherichia coli: all has not been said and done.

During recent years new systems involved in iron transport were identified in the old workhorse Escherichia coli (and in other enterobacteria). This came as a bit of a surprise because one might think transport of this essential trace element was already thoroughly studied. Moreover, it appears that iron homeostasis consists not only of uptake but also of efflux of this potentially toxic redox-active metal. New findings in E. coli will be discussed and compared to the situation in other bacteria.