Literature DB >> 16718329

Desymmetrization of diols by a tandem oxidation/Wittig olefination reaction.

David J Phillips1, Kathryn S Pillinger, Wei Li, Angela E Taylor, Andrew E Graham.   

Abstract

Diols are desymmetrized by a tandem oxidation/Wittig olefination to give alpha,beta-unsaturated hydroxy esters without the requirement for protecting group strategies; the alpha,beta-unsaturated hydroxy esters are transformed into dienyl diesters using a second oxidation/Wittig olefination sequence using PCC.

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Year:  2006        PMID: 16718329     DOI: 10.1039/b602329k

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN: 1359-7345            Impact factor:   6.222


  2 in total

1.  Coibacins A and B: total synthesis and stereochemical revision.

Authors:  Vânia M T Carneiro; Carolina M Avila; Marcy J Balunas; William H Gerwick; Ronaldo A Pilli
Journal:  J Org Chem       Date:  2014-01-09       Impact factor: 4.354

2.  An Efficient, Eco-friendly and Sustainable One-Pot Synthesis of 3,4-Dihydropyrimidin-2(1H)-ones Directly from Alcohols Catalyzed by Heteropolyanion-Based Ionic Liquids.

Authors:  Renzhong Fu; Yang Yang; Xudong Ma; Yu Sun; Jin Li; Hang Gao; Huaxing Hu; Xiaojun Zeng; Jun Yi
Journal:  Molecules       Date:  2017-09-11       Impact factor: 4.411

  2 in total

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