Literature DB >> 1671796

Correlation of mutations of oncogene C-Ha-ras at codon 12 with metastasis and survival of gastric cancer patients.

G R Deng1, X H Liu, J R Wang.   

Abstract

Mutations of c-Ha-ras at codon 12 were detected from 11 out of 27 fresh tissues and cell-lines of human gastric cancer patients using PCR-restriction analysis. Further statistical investigation showed that the presence of point mutations was related to the distal metastases and the survival time of gastric cancer patients after surgical operations.

Entities:  

Mesh：

Year:  1991        PMID： 1671796

Source DB:  PubMed          Journal:  Oncogene Res        ISSN： 0890-6467


  7 in total

Review 1.  Preoperative staging of gastric cancer as precondition for multimodal treatment.

Authors:  A Sendler; H J Dittler; H Feussner; H Nekarda; E Bollschweiler; U Fink; H Helmberger; H Höfler; J R Siewert
Journal:  World J Surg       Date:  1995 Jul-Aug       Impact factor: 3.352

2.  The role of ras gene mutation in gastric cancer and precancerous lesions.

Authors:  Y Hao; J Zhang; Y Lu; C Yi; W Qian; J Cui
Journal:  J Tongji Med Univ       Date:  1998

3.  Expression of oncoproteins in primary human non-small cell lung cancer and incidence of metastases.

Authors:  M Volm; P Drings; W Wodrich; G van Kaick
Journal:  Clin Exp Metastasis       Date:  1993-07       Impact factor: 5.150

4.  Absence of ras gene mutations in early gastric carcinomas.

Authors:  M E Craanen; P Blok; B Top; L Boerrigter; W Dekker; G J Offerhaus; G N Tytgat; S Rodenhuis
Journal:  Gut       Date:  1995-12       Impact factor: 23.059

5.  Studies on the relationship between the point mutation of ras oncogenes and the prognosis of patients with gastric cancer.

Authors:  D C Fang; Y H Luo; R Lu; W W Liu
Journal:  World J Gastroenterol       Date:  1997-03-15       Impact factor: 5.742

6.  Interference with endogenous ras function inhibits cellular responses to wounding.

Authors:  R G Sosnowski; S Feldman; J R Feramisco
Journal:  J Cell Biol       Date:  1993-04       Impact factor: 10.539

7.  Association between H-RAS T81C genetic polymorphism and gastrointestinal cancer risk: a population based case-control study in China.

Authors:  Yongjing Zhang; Mingjuan Jin; Bing Liu; Xinyuan Ma; Kaiyan Yao; Qilong Li; Kun Chen
Journal:  BMC Cancer       Date:  2008-09-10       Impact factor: 4.430
  7 in total

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