Literature DB >> 16715707

[Effect of exogenous DNA on the growth of transplantable tumors].

V P Nikolin, N A Popova, T E Sebeleva, D N Strunkin, V A Rogachev, D V Semënov, S S Bogachev, L A Iakubov, M A Shurdov.   

Abstract

Using transplantable Ehrlich ascites tumor, hepatoma HA-1 and Lewis carcinoma it was shown, that preparations of fragmented genomic DNA can more or less effectively inhibit such tumors as well as the growth of their metastases. Such effects were produced by DNA preparations derived from tissues of mice, both syngeneic or allogeneic to tumor-bearer, as well as from human tissues.

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Year:  2006        PMID: 16715707

Source DB:  PubMed          Journal:  Vopr Onkol        ISSN: 0507-3758


  1 in total

1.  A strategy of tumor treatment in mice with doxorubicin-cyclophosphamide combination based on dendritic cell activation by human double-stranded DNA preparation.

Authors:  Ekaterina A Alyamkina; Valeriy P Nikolin; Nelly A Popova; Evgenia V Dolgova; Anastasia S Proskurina; Konstantin E Orishchenko; Yaroslav R Efremov; Elena R Chernykh; Alexandr A Ostanin; Sergey V Sidorov; Dmitriy M Ponomarenko; Stanislav N Zagrebelniy; Sergey S Bogachev; Mikhail A Shurdov
Journal:  Genet Vaccines Ther       Date:  2010-11-01
  1 in total

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