Literature DB >> 16714267

Long term functional and structural outcomes of laser therapy for retinopathy of prematurity.

E McLoone1, M O'Keefe, S McLoone, B Lanigan.   

Abstract

AIMS: To assess the long term functional and structural outcomes of premature babies who received diode laser photocoagulation for threshold retinopathy of prematurity (ROP).
METHODS: 25 patients (43 eyes) treated with laser were recalled for assessment at a mean follow up of 11 years. A further seven patients (14 eyes) with subthreshold ROP, which had regressed spontaneously without laser treatment, were also examined. All children underwent distance acuity, near acuity, contrast sensitivity (CS), and colour vision assessments followed by a dilated fundal examination and cycloplegic autorefraction.
RESULTS: The laser treated eyes had a mean distance visual acuity of 0.37 logMAR, a mean near visual acuity of 0.39 logMAR, a mean contrast sensitivity of 1.49 log CS units, and a mean spherical equivalent of -2.10D. An unfavourable distance visual acuity outcome occurred in five eyes (13.5%). An unfavourable near visual acuity outcome was also noted in the five eyes (13.5%) with poor distance visual outcome. 7% had an unfavourable structural outcome. On comparison with the control group, there was no significant difference in near acuity, CS, refraction, or colour vision between the two groups. However, there was a statistically significant difference in terms of distance visual acuity (p = 0.03).
CONCLUSIONS: Laser treated eyes with favourable structural outcome have a good visual outcome. The results show a long term benefit from diode laser photocoagulation in preserving distance and near vision in eyes with threshold ROP.

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Mesh:

Year:  2006        PMID: 16714267      PMCID: PMC1860208          DOI: 10.1136/bjo.2005.068304

Source DB:  PubMed          Journal:  Br J Ophthalmol        ISSN: 0007-1161            Impact factor:   4.638


  19 in total

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Authors:  J Ohlsson; G Villarreal; A Sjöström; M Abrahamsson; J Sjöstrand
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2.  Visual impairment in very low birthweight children.

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3.  Randomized comparison of diode laser photocoagulation versus cryotherapy for threshold retinopathy of prematurity: seven-year outcome.

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Journal:  Am J Ophthalmol       Date:  2001-07       Impact factor: 5.258

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Authors:  M O'Keefe; J O'Reilly; B Lanigan
Journal:  Br J Ophthalmol       Date:  1998-11       Impact factor: 4.638

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Authors:  Eugene Y J Ng; Brian P Connolly; J Arch McNamara; Carl D Regillo; James F Vander; William Tasman
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Authors: 
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7.  Contrast sensitivity at age 10 years in children who had threshold retinopathy of prematurity.

Authors: 
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8.  Randomized comparison of diode laser photocoagulation versus cryotherapy for threshold retinopathy of prematurity: 3-year outcome.

Authors:  J E White; M X Repka
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6.  Delayed luminance and chromatic contrast sensitivity in infants with spontaneously regressed retinopathy of prematurity.

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7.  Refractive and Visual Outcome after Laser-Treated Retinopathy of Prematurity in Western Romania.

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9.  Long term visual outcomes in laser treated threshold retinopathy of prematurity in Central Saudi Arabia.

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Review 10.  Role of the retinal vascular endothelial cell in ocular disease.

Authors:  Arpita S Bharadwaj; Binoy Appukuttan; Phillip A Wilmarth; Yuzhen Pan; Andrew J Stempel; Timothy J Chipps; Eric E Benedetti; David O Zamora; Dongseok Choi; Larry L David; Justine R Smith
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