| Literature DB >> 16713559 |
Esben Lorentzen1, Elena Conti.
Abstract
Exosomes and proteasomes are macromolecular complexes that posttranscriptionally regulate gene expression by degrading mRNAs and proteins, respectively. Although the two complexes act on different substrates and are composed of different subunits, they share a similar barrel-like architecture that appears to have evolved to restrict substrate access and prevent indiscriminate degradation.Mesh:
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Year: 2006 PMID: 16713559 DOI: 10.1016/j.cell.2006.05.002
Source DB: PubMed Journal: Cell ISSN: 0092-8674 Impact factor: 41.582