Literature DB >> 16713392

Should trans fatty acids be viewed as membrane-active drugs?

Arnold M Katz1.   

Abstract

Trans fatty acids (TFA) can modify cellular function by interacting with hydrophobic regions of membrane proteins. Because these interactions resemble those of pharmacological agents, it might be appropriate to view TFA as drugs.

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Year:  2006        PMID： 16713392     DOI： 10.1016/j.atherosclerosissup.2006.04.009

Source DB:  PubMed          Journal:  Atheroscler Suppl        ISSN： 1567-5688            Impact factor:   3.235


  4 in total

1.  Trans fatty acids exacerbate dextran sodium sulphate-induced colitis by promoting the up-regulation of macrophage-derived proinflammatory cytokines involved in T helper 17 cell polarization.

Authors:  Y Okada; Y Tsuzuki; H Sato; K Narimatsu; R Hokari; C Kurihara; C Watanabe; K Tomita; S Komoto; A Kawaguchi; S Nagao; S Miura
Journal:  Clin Exp Immunol       Date:  2013-12       Impact factor: 4.330

2.  A mechanism by which dietary trans fats cause atherosclerosis.

Authors:  Chun-Lin Chen; Laura H Tetri; Brent A Neuschwander-Tetri; Shuan Shian Huang; Jung San Huang
Journal:  J Nutr Biochem       Date:  2010-10-30       Impact factor: 6.048

3.  Effect of industrially produced trans fat on markers of systemic inflammation: evidence from a randomized trial in women.

Authors:  Nathalie T Bendsen; Steen Stender; Pal B Szecsi; Steen B Pedersen; Samar Basu; Lars I Hellgren; John W Newman; Thomas M Larsen; Steen B Haugaard; Arne Astrup
Journal:  J Lipid Res       Date:  2011-07-27       Impact factor: 5.922

Review 4.  Trans-fatty acids and nonlipid risk factors.

Authors:  Sarah K Wallace; Dariush Mozaffarian
Journal:  Curr Atheroscler Rep       Date:  2009-11       Impact factor: 5.113
  4 in total

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