| Literature DB >> 16712568 |
Sylvan Rego1, Andrew Kemp, Melanie Wong, Paul Knight.
Abstract
Omenn syndrome is a severe combined immunodeficiency with features of generalised erythroderma alopecia and evidence of Th2 inflammation (eosinophilia and raised IgE). We describe a differential effect of 2 calcineurin inhibitors, cyclosporine A (CsA) and tacrolimus, with CsA rapidly improving the erythroderma and lymphocytosis but tacrolimus having little effect.Entities:
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Year: 2006 PMID： 16712568 DOI： 10.1111/j.1440-1754.2006.00863.x
Source DB: PubMed Journal: J Paediatr Child Health ISSN： 1034-4810 Impact factor: 1.954