Literature DB >> 16710088

Dementia in subjects aged 75 years or over within the PAQUID cohort: prevalence and burden by severity.

Catherine Helmer1, Karine Pérès, Luc Letenneur, Luis Miguel Guttiérez-Robledo, Hanta Ramaroson, Pascale Barberger-Gateau, Colette Fabrigoule, Jean-Marc Orgogozo, Jean-François Dartigues.   

Abstract

BACKGROUND/AIMS: To analyze the prevalence of dementia by severity and to describe the sociodemographic characteristics of people with dementia in the community, as well as the consequences of this disease in terms of disability and institutionalization.
METHODS: This study was based on the PAQUID community-based cohort study of 1,461 subjects aged 75 years or over. Severity of dementia was assessed using the Mini-Mental State Examination (MMSE).
RESULTS: The prevalence of dementia was estimated to be 17.8%, with about 43% at a moderately severe or more severe stage of the disease (MMSE <or= 15). About 39% of the people with dementia lived in an institution. Among the institutionalized residents, 71.6% were diagnosed as demented. About 57% of the people with dementia were ADL disabled. In this over-75 population, people with dementia accounted for 74% of the ADL-disabled subjects. The consequences of dementia were particularly frequent among the subjects who were at least at a moderately severe stage of dementia, with 59.6% of them living in institution and 87.2% being ADL disabled.
CONCLUSION: These results confirm the high prevalence of dementia in subjects aged over 75 and illustrate the devastating consequences of this disease in terms of disability and institutionalization.

Entities:  

Mesh:

Year:  2006        PMID: 16710088     DOI: 10.1159/000093459

Source DB:  PubMed          Journal:  Dement Geriatr Cogn Disord        ISSN: 1420-8008            Impact factor:   2.959


  12 in total

Review 1.  Early prevention at public health issue.

Authors:  J F Dartigues; C Helmer; K Peres; P Cowppli Bony; S Auriacombe; J M Orgogozo
Journal:  J Nutr Health Aging       Date:  2008-01       Impact factor: 4.075

2.  Effects of Physical Activity in Nursing Home Residents with Dementia: A Randomized Controlled Trial.

Authors:  Marinda Henskens; Ilse M Nauta; Marieke C A van Eekeren; Erik J A Scherder
Journal:  Dement Geriatr Cogn Disord       Date:  2018-08-24       Impact factor: 2.959

3.  Comorbidity and clinical features in elderly patients with dementia: differences according to dementia severity.

Authors:  F Formiga; I Fort; M J Robles; S Riu; O Sabartes; E Barranco; J Catena
Journal:  J Nutr Health Aging       Date:  2009-05       Impact factor: 4.075

4.  Balneotherapy, prevention of cognitive decline and care the Alzheimer patient and his family: outcome of a multidisciplinary workgroup.

Authors:  M Secher; M Soto; S Gillette; S Andrieu; H Villars; B Vellas; C Tabone; J-B Chareyras; O Dubois; C-F Roques; B Dubois
Journal:  J Nutr Health Aging       Date:  2009-11       Impact factor: 4.075

5.  Addressing the challenges to successful recruitment and retention in Alzheimer's disease clinical trials.

Authors:  Joshua D Grill; Jason Karlawish
Journal:  Alzheimers Res Ther       Date:  2010-12-21       Impact factor: 6.982

6.  Differential associations of plasma lipids with incident dementia and dementia subtypes in the 3C Study: A longitudinal, population-based prospective cohort study.

Authors:  Sabrina Schilling; Christophe Tzourio; Aïcha Soumaré; Sara Kaffashian; Jean-François Dartigues; Marie-Laure Ancelin; Cécilia Samieri; Carole Dufouil; Stéphanie Debette
Journal:  PLoS Med       Date:  2017-03-28       Impact factor: 11.069

7.  Mood and behavioral problems are important predictors of quality of life of nursing home residents with moderate to severe dementia: A cross-sectional study.

Authors:  Marinda Henskens; Ilse M Nauta; Susan Vrijkotte; Katja T Drost; Maarten V Milders; Erik J A Scherder
Journal:  PLoS One       Date:  2019-12-20       Impact factor: 3.240

Review 8.  Oxidative stress and epilepsy: literature review.

Authors:  Carlos Clayton Torres Aguiar; Anália Barbosa Almeida; Paulo Victor Pontes Araújo; Rita Neuma Dantas Cavalcante de Abreu; Edna Maria Camelo Chaves; Otoni Cardoso do Vale; Danielle Silveira Macêdo; David John Woods; Marta Maria de França Fonteles; Silvania Maria Mendes Vasconcelos
Journal:  Oxid Med Cell Longev       Date:  2012-07-14       Impact factor: 6.543

9.  A transient awakening of a patient with Alzheimer's disease that questions our practice.

Authors:  Frédéric Bloch
Journal:  Clin Case Rep       Date:  2016-03-02

10.  Telemedicine for the management of neuropsychiatric symptoms in long-term care facilities: the DETECT study, methods of a cluster randomised controlled trial to assess feasibility.

Authors:  Antoine Piau; Fati Nourhashemi; Adélaïde De Mauléon; Achille Tchalla; Claude Vautier; Bruno Vellas; Maryline Duboue; Nadège Costa; Pierre Rumeau; Benoit Lepage; Maria Soto Martin
Journal:  BMJ Open       Date:  2018-06-12       Impact factor: 2.692

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.