Literature DB >> 16710019

Is there a role for the irreversible epidermal growth factor receptor inhibitor EKB-569 in the treatment of cancer? A mutation-driven question.

Jose Baselga.   

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Year:  2006        PMID: 16710019     DOI: 10.1200/JCO.2005.05.3785

Source DB:  PubMed          Journal:  J Clin Oncol        ISSN: 0732-183X            Impact factor:   44.544


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  2 in total

1.  Chronic pharmacologic inhibition of EGFR leads to cardiac dysfunction in C57BL/6J mice.

Authors:  Cordelia J Barrick; Ming Yu; Hann-Hsiang Chao; David W Threadgill
Journal:  Toxicol Appl Pharmacol       Date:  2008-03-07       Impact factor: 4.219

2.  Irreversible EGFR inhibitor EKB-569 targets low-LET γ-radiation-triggered rel orchestration and potentiates cell death in squamous cell carcinoma.

Authors:  Natarajan Aravindan; Charles R Thomas; Sheeja Aravindan; Aswathi S Mohan; Jamunarani Veeraraghavan; Mohan Natarajan
Journal:  PLoS One       Date:  2011-12-29       Impact factor: 3.240

  2 in total

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