| Literature DB >> 16709185 |
S Kurup1, A Abramsson, J P Li, U Lindahl, L Kjellen, C Betsholtz, H Gerhardt, D Spillmann.
Abstract
HS (heparan sulphate) plays a key role in angiogenesis, by interacting with growth factors required in the process. It has been proposed that HS controls the diffusion, and thus the availability, of platelet-derived growth factor B that is needed for pericyte recruitment around newly formed capillaries. The present paper summarizes our studies on the importance of HS structure in this regulatory process.Entities:
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Year: 2006 PMID： 16709185 DOI： 10.1042/BST0340454
Source DB: PubMed Journal: Biochem Soc Trans ISSN： 0300-5127 Impact factor: 5.407