Literature DB >> 1670853

The axilla: not a no-go zone.

I S Fentiman1, R E Mansel.   

Abstract

Many surgeons, particularly in the UK, give inadequate primary treatment to patients with operable breast cancer. For spurious reasons they regard axillary clearance as unnecessarily extensive surgery and rely instead upon total mastectomy or tumour excision and node sampling, with or without postoperative radiotherapy. But it is now clear that relapse-free and overall survival can be improved by appropriate adjuvant therapy. Thus inadequate exploration of the axilla is doubly unjustified. Not only is there the obvious risk of failure to remove nodes that contain metastases--so that some patients are deprived of cure by primary treatment--but the extent of tumour spread will be inadequately assessed in many more patients, with the risk that they may not receive appropriate adjuvant treatment.

Entities:  

Mesh:

Year:  1991        PMID: 1670853     DOI: 10.1016/0140-6736(91)92172-x

Source DB:  PubMed          Journal:  Lancet        ISSN: 0140-6736            Impact factor:   79.321


  24 in total

1.  Prognostic value of the interpectoral lymph nodes in breast cancer. A 20-year survival study.

Authors:  A García-Vilanova Comas; A García Vilanova; E Fuster-Diana; N Martínez-Alzamora; Jm Fernández-Tena; J García-Vilanova Comas; M García-Vilanova Comas
Journal:  Clin Transl Oncol       Date:  2006-02       Impact factor: 3.405

Review 2.  General surgery.

Authors:  I Taylor
Journal:  Postgrad Med J       Date:  1991-10       Impact factor: 2.401

3.  Axillary dissection in primary breast cancer.

Authors: 
Journal:  BMJ       Date:  1991-03-09

4.  Intraoperative assessment of axillary lymph node metastases in operable breast cancer.

Authors:  M Noguchi; M Minami; M Earashi; T Taniya; I Miyazaki; Y Mizukami; A Nonomura
Journal:  Breast Cancer Res Treat       Date:  1996       Impact factor: 4.872

5. 

Authors:  P Schäfer
Journal:  Arch Gynecol Obstet       Date:  1995-12       Impact factor: 2.344

6. 

Authors:  J C Rageth
Journal:  Arch Gynecol Obstet       Date:  1995-12       Impact factor: 2.344

7.  A survey of the management of breast cancer in England and Wales.

Authors:  S A Harries; R N Lawrence; R Scrivener; N R Fieldman; M W Kissin
Journal:  Ann R Coll Surg Engl       Date:  1996-05       Impact factor: 1.891

8.  Long-term outcomes of breast cancer in women aged 30 years or younger, based on family history, pathology and BRCA1/BRCA2/TP53 status.

Authors:  D G R Evans; A Moran; R Hartley; J Dawson; B Bulman; F Knox; A Howell; F Lalloo
Journal:  Br J Cancer       Date:  2010-03-16       Impact factor: 7.640

Review 9.  Current perspectives in the use of monoclonal antibodies for detection and treatment of head and neck tumors.

Authors:  J Quak; G van Dongen
Journal:  Eur Arch Otorhinolaryngol       Date:  1994       Impact factor: 2.503

10.  Evaluating the breast screening programme: the need for surgical audit.

Authors:  F Kee; D Gorman; W Odling-Smee
Journal:  J R Soc Med       Date:  1993-02       Impact factor: 5.344

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