Literature DB >> 16707276

Progress in in silico functional genomics: the malaria Metabolic Pathways database.

Hagai Ginsburg1.   

Abstract

Genomic, transcriptomic and proteomic data can be turned into biologically meaningful information if they are synthesized into processes. Such amalgamation has been done for the most virulent malaria parasite Plasmodium falciparum in the Metabolic Pathways database. The dialectics of construction of metabolic pathways and other biological processes using this database is presented here. Additional features, such as links to other databases and the incorporation of transcriptomic clocks, are elucidated. Comparison of Metabolic Pathways to other similar databases is analyzed.

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Year:  2006        PMID: 16707276     DOI: 10.1016/j.pt.2006.04.008

Source DB:  PubMed          Journal:  Trends Parasitol        ISSN: 1471-4922


  50 in total

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Journal:  J Lipid Res       Date:  2010-01       Impact factor: 5.922

2.  An in silico strategy for identification of novel drug targets against Plasmodium falciparum.

Authors:  Subhashree Rout; Namrata Priyadarshini Patra; Rajani Kanta Mahapatra
Journal:  Parasitol Res       Date:  2017-07-28       Impact factor: 2.289

3.  Biosynthesis of GDP-fucose and other sugar nucleotides in the blood stages of Plasmodium falciparum.

Authors:  Sílvia Sanz; Giulia Bandini; Diego Ospina; Maria Bernabeu; Karina Mariño; Carmen Fernández-Becerra; Luis Izquierdo
Journal:  J Biol Chem       Date:  2013-04-24       Impact factor: 5.157

4.  Antimalarial drug targets in Plasmodium falciparum predicted by stage-specific metabolic network analysis.

Authors:  Carola Huthmacher; Andreas Hoppe; Sascha Bulik; Hermann-Georg Holzhütter
Journal:  BMC Syst Biol       Date:  2010-08-31

5.  Reconstruction and flux-balance analysis of the Plasmodium falciparum metabolic network.

Authors:  Germán Plata; Tzu-Lin Hsiao; Kellen L Olszewski; Manuel Llinás; Dennis Vitkup
Journal:  Mol Syst Biol       Date:  2010-09-07       Impact factor: 11.429

6.  Comparative Genomics and Systems Biology of Malaria Parasites Plasmodium.

Authors:  Hong Cai; Zhan Zhou; Jianying Gu; Yufeng Wang
Journal:  Curr Bioinform       Date:  2012-12-01       Impact factor: 3.543

7.  The transcriptome of Plasmodium vivax reveals divergence and diversity of transcriptional regulation in malaria parasites.

Authors:  Zbynek Bozdech; Sachel Mok; Guangan Hu; Mallika Imwong; Anchalee Jaidee; Bruce Russell; Hagai Ginsburg; Francois Nosten; Nicholas P J Day; Nicholas J White; Jane M Carlton; Peter R Preiser
Journal:  Proc Natl Acad Sci U S A       Date:  2008-10-13       Impact factor: 11.205

8.  A combined transcriptome and proteome survey of malaria parasite liver stages.

Authors:  Alice S Tarun; Xinxia Peng; Ronald F Dumpit; Yuko Ogata; Hilda Silva-Rivera; Nelly Camargo; Thomas M Daly; Lawrence W Bergman; Stefan H I Kappe
Journal:  Proc Natl Acad Sci U S A       Date:  2008-01-02       Impact factor: 11.205

9.  FMM: a web server for metabolic pathway reconstruction and comparative analysis.

Authors:  Chih-Hung Chou; Wen-Chi Chang; Chih-Min Chiu; Chih-Chang Huang; Hsien-Da Huang
Journal:  Nucleic Acids Res       Date:  2009-04-28       Impact factor: 16.971

10.  PlasmoDB: a functional genomic database for malaria parasites.

Authors:  Cristina Aurrecoechea; John Brestelli; Brian P Brunk; Jennifer Dommer; Steve Fischer; Bindu Gajria; Xin Gao; Alan Gingle; Greg Grant; Omar S Harb; Mark Heiges; Frank Innamorato; John Iodice; Jessica C Kissinger; Eileen Kraemer; Wei Li; John A Miller; Vishal Nayak; Cary Pennington; Deborah F Pinney; David S Roos; Chris Ross; Christian J Stoeckert; Charles Treatman; Haiming Wang
Journal:  Nucleic Acids Res       Date:  2008-10-28       Impact factor: 16.971

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