Literature DB >> 16704396

Brief report: Reducing inappropriate usage of stress ulcer prophylaxis among internal medicine residents. A practice-based educational intervention.

Joshua D Liberman1, Chad T Whelan.   

Abstract

BACKGROUND: Many inpatients receive stress ulcer prophylaxis (SUP) inappropriately. This indiscriminate usage increases costs and avoidable side-effects. Practice-based learning and improvement (PBLI) methodology may improve compliance with published guidelines.
OBJECTIVE: To investigate the response of internal medicine residents to an educational intervention regarding SUP.
DESIGN: A prospective, pre and postintervention cohort study using an educational intervention based on PBLI. PATIENTS: Three groups of consecutively admitted patients (1 group preintervention and 2 groups postintervention) on the medicine ward at a University Hospital. MAIN OUTCOME MEASURE: Rates of inappropriate SUP prescription and discharge with an inappropriate prescription.
RESULTS: One month after the intervention, inappropriate prophylaxis was significantly decreased (59% pre, 29% postintervention, P<.002). The rate of discharge with an inappropriate prescription also decreased, but was not significant (25% pre, 14% postintervention, P=.14). In the 6-month postintervention cohort, inappropriate SUP remained lower (59% pre, 33% postintervention, P<.007). The rate of discharge with an inappropriate prescription was also significantly lower (25% pre, 7% postintervention, P<.009).
CONCLUSION: Practice-based learning and improvement can improve compliance with published guidelines, and change practice patterns. After the intervention, both inappropriate prophylaxis and inappropriate prescriptions upon discharge were reduced. Importantly, the intervention was sustained, transmitted across academic years to a new class of interns who had not directly experienced the intervention.

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Year:  2006        PMID: 16704396      PMCID: PMC1484795          DOI: 10.1111/j.1525-1497.2006.00435.x

Source DB:  PubMed          Journal:  J Gen Intern Med        ISSN: 0884-8734            Impact factor:   5.128


  12 in total

1.  ASHP Therapeutic Guidelines on Stress Ulcer Prophylaxis. ASHP Commission on Therapeutics and approved by the ASHP Board of Directors on November 14, 1998.

Authors: 
Journal:  Am J Health Syst Pharm       Date:  1999-02-15       Impact factor: 2.637

Review 2.  Why don't physicians follow clinical practice guidelines? A framework for improvement.

Authors:  M D Cabana; C S Rand; N R Powe; A W Wu; M H Wilson; P A Abboud; H R Rubin
Journal:  JAMA       Date:  1999-10-20       Impact factor: 56.272

3.  Overuse of acid-suppressive therapy in hospitalized patients.

Authors:  R J Nardino; R J Vender; P N Herbert
Journal:  Am J Gastroenterol       Date:  2000-11       Impact factor: 10.864

4.  National survey of stress ulcer prophylaxis.

Authors:  N P Lam; P D Lê; S Y Crawford; S Patel
Journal:  Crit Care Med       Date:  1999-01       Impact factor: 7.598

5.  Gastrointestinal bleeding in the hospitalized patient: a case-control study to assess risk factors, causes, and outcome.

Authors:  J P Terdiman; J W Ostroff
Journal:  Am J Med       Date:  1998-04       Impact factor: 4.965

6.  Impact of trauma stress ulcer prophylaxis guidelines on drug cost and frequency of major gastrointestinal bleeding.

Authors:  J W Devlin; K S Claire; S A Dulchavsky; J G Tyburski
Journal:  Pharmacotherapy       Date:  1999-04       Impact factor: 4.705

7.  Strategies to improve compliance with evidence-based clinical management guidelines.

Authors:  H L Frankel; M K FitzPatrick; S Gaskell; W S Hoff; M F Rotondo; C W Schwab
Journal:  J Am Coll Surg       Date:  1999-12       Impact factor: 6.113

8.  Risk factors for gastrointestinal bleeding in critically ill patients. Canadian Critical Care Trials Group.

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Journal:  N Engl J Med       Date:  1994-02-10       Impact factor: 91.245

Review 9.  Prophylaxis for stress-related gastrointestinal hemorrhage: a cost effectiveness analysis.

Authors:  T Ben-Menachem; B D McCarthy; R Fogel; R M Schiffman; R V Patel; B J Zarowitz; D R Nerenz; R S Bresalier
Journal:  Crit Care Med       Date:  1996-02       Impact factor: 7.598

10.  Survey of stress ulcer prophylaxis.

Authors: 
Journal:  Crit Care       Date:  1999       Impact factor: 9.097

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  12 in total

1.  Stress ulcer prophylaxis guidelines: Are they being implemented in Lebanese health care centers?

Authors:  Abeer Zeitoun; Maya Zeineddine; Hani Dimassi
Journal:  World J Gastrointest Pharmacol Ther       Date:  2011-08-06

2.  Pharmacy student impact on inappropriate prescribing of acid suppressive therapy.

Authors:  Katherine M Carey; Jason E Cross; Matthew A Silva; Mihaela S Stefan; Michael B Rothberg
Journal:  Am J Pharm Educ       Date:  2011-11-10       Impact factor: 2.047

3.  Improving appropriateness of acid-suppressive medication use via computerized clinical decision support.

Authors:  Shoshana J Herzig; Jamey R Guess; David B Feinbloom; May Adra; Kevin A Afonso; Michael D Howell; Edward R Marcantonio
Journal:  J Hosp Med       Date:  2015-01       Impact factor: 2.960

4.  Impact of Stress Ulcer Prophylaxis Discontinuation Guidance in Mechanically Ventilated, Critically Ill Patients: A Pre-Post Cohort Study.

Authors:  Christopher A Jones; Kevin D Betthauser; Bryan D Lizza; Paul A Juang; Scott T Micek; Marin H Kollef
Journal:  Hosp Pharm       Date:  2021-12-07

5.  Current Opinions on Stress-Related Mucosal Disease Prevention in Canadian Pediatric Intensive Care Units.

Authors:  Jérôme Ouellet; Dennis Bailey; Marie-Ève Samson
Journal:  J Pediatr Pharmacol Ther       Date:  2015 Jul-Aug

6.  Use of acid suppressive therapy in hospitalized non-critically ill patients.

Authors:  Marwan Sheikh-Taha; Sarah Alaeddine; Julie Nassif
Journal:  World J Gastrointest Pharmacol Ther       Date:  2012-12-06

7.  Physicians' opinions of stress ulcer prophylaxis: survey results from a large urban medical center.

Authors:  Charles P Koczka; Laura B Geraldino-Pardilla; Adam J Goodman
Journal:  Dig Dis Sci       Date:  2012-10-12       Impact factor: 3.199

8.  IBCD: development and testing of a checklist to improve quality of care for hospitalized general medical patients.

Authors:  Anthony V Aspesi; Greg E Kauffmann; Andrew M Davis; Elizabeth M Schulwolf; Valerie G Press; Kristen L Stupay; Janey J Lee; Vineet M Arora
Journal:  Jt Comm J Qual Patient Saf       Date:  2013-04

9.  Impact of targeted educational interventions on appropriateness of stress ulcer prophylaxis in critically ill adults.

Authors:  Drayton A Hammond; Catherine A Killingsworth; Jacob T Painter; Rose E Pennick; Kshitij Chatterjee; Bradley Boye; Nikhil Meena
Journal:  Pharm Pract (Granada)       Date:  2017-08-15

10.  Identifying Risk Factors Associated with Inappropriate Use of Acid Suppressive Therapy at a Community Hospital.

Authors:  Amandeep Singh; Vijay Bodukam; Kirit Saigal; Jaya Bahl; Yvette Wang; Alexandra Hanlon; Yinghui Lu; Michael Davis
Journal:  Gastroenterol Res Pract       Date:  2016-10-12       Impact factor: 2.260

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