| Literature DB >> 16702966 |
Abstract
Previous studies have localized the psoriasis susceptibility 1 (PSORS1) locus to the proximal major histocompatibility complex class I region, but approximately a dozen genes in the candidate region have thus far been genetically inseparable. According to a team of researchers in the United States and Germany, the primary genetic association has now been worked out, implicating HLA-Cw6 "after all." The results integrate genetics and immunology, further reinforcing our emerging understanding of psoriasis.Entities:
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Year: 2006 PMID： 16702966 DOI： 10.1038/sj.jid.5700357
Source DB: PubMed Journal: J Invest Dermatol ISSN： 0022-202X Impact factor: 8.551