Literature DB >> 16701766

COPD as a multicomponent disease: inventory of dyspnoea, underweight, obesity and fat free mass depletion in primary care.

Lotte M G Steuten1, Eva C Creutzberg, Hubertus J M Vrijhoef, Emiel F Wouters.   

Abstract

AIMS: To describe the distribution of COPD disease severity in primary care based on airway obstruction, and to assess the extent to which dyspnoea scores, body mass index (BMI) and fat free mass (FFM) index contribute to the distribution of COPD severity in primary care.
DESIGN: Cross sectional population-based study.
METHODS: 317 patients with COPD were recruited from an outpatient disease management programme. Prevalence of moderate to severe dyspnoea, underweight, obesity and FFM depletion by GOLD stage were measured.
RESULTS: According to GOLD guidelines, 29% of patients had mild COPD, 48% moderate, 17% severe and 5% very severe. A substantial number of patients classified as GOLD stage 2 reported severe dyspnoea (28.1%) and/or suffered from FFM depletion (16.3%). Prevalence of low body weight strongly increased in GOLD stage 4. Prevalence of obesity is highest in GOLD stages 1 and 2.
CONCLUSION: The use of a multidimensional grading system, taking into account dyspnoea as well as the nutritional status of COPD patients, is likely to influence the distribution of disease severity in a primary care population. This might have implications for prevention, non-medical treatment, and estimates of health care utilisation in primary care.

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Year:  2005        PMID: 16701766      PMCID: PMC6730686          DOI: 10.1016/j.pcrj.2005.09.001

Source DB:  PubMed          Journal:  Prim Care Respir J        ISSN: 1471-4418


  47 in total

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Review 5.  Managing older patients with coexistent asthma and chronic obstructive pulmonary disease: diagnostic and therapeutic challenges.

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6.  Obesity Is Associated With Increased Morbidity in Moderate to Severe COPD.

Authors:  Allison A Lambert; Nirupama Putcha; M Bradley Drummond; Aladin M Boriek; Nicola A Hanania; Victor Kim; Gregory L Kinney; Merry-Lynn N McDonald; Emily P Brigham; Robert A Wise; Meredith C McCormack; Nadia N Hansel
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7.  Effect of obesity on constant workrate exercise in hyperinflated men with COPD.

Authors:  Louis Laviolette; Francesco Sava; Denis E O'Donnell; Katherine A Webb; Alan L Hamilton; Steven Kesten; François Maltais
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Review 8.  Systemic inflammation in chronic obstructive pulmonary disease: may adipose tissue play a role? Review of the literature and future perspectives.

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Journal:  Mediators Inflamm       Date:  2010-04-20       Impact factor: 4.711

9.  Obesity and respiratory diseases.

Authors:  Christopher Zammit; Helen Liddicoat; Ian Moonsie; Himender Makker
Journal:  Int J Gen Med       Date:  2010-10-20

10.  Systemic impairment in relation to disease burden in patients with moderate COPD eligible for a lifestyle program. Findings from the INTERCOM trial.

Authors:  Carel R van Wetering; Floortje E van Nooten; Stijn J M Mol; Martine Hoogendoorn; Maureen P M H Rutten-Van Mölken; Annemie M Schols
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