Literature DB >> 16701705

Patterns of corticosteroid medication use: non-adherence can be effective in milder asthma.

Colin J Greaves1, Michael E Hyland, David M G Halpin, Susan Blake, David Seamark.   

Abstract

AIMS: To identify specific patterns of corticosteroid use and examine their relationship with asthma outcomes.
METHODS: An adherence questionnaire was developed and applied in a population-based observational survey; this compared unscheduled care visits and asthma quality of life for adherent and non-adherent patient groups within 176 patients from a semi-rural UK practice.
RESULTS: Three main patterns of medication use were identified: Regular; Regular-but-less (Low-Dosing); and Symptom-Directed variation. For mild-to-moderate asthma (BTS treatment step 2), non-adherence produced acceptable outcomes, not significantly different from outcomes for adherent patients. For more severe asthma, regular adherence was more effective, resulting in significantly less unscheduled visits.
CONCLUSIONS: The results suggest that flexible 'symptom-directed' medication use and patient-initiated dose reduction may be viable alternatives to regular medication for a number of lower severity patients. For milder asthma, clinicians should perhaps focus their efforts on patients with poor asthma outcomes, rather than poor adherence.

Entities:  

Year:  2005        PMID: 16701705      PMCID: PMC6743549          DOI: 10.1016/j.pcrj.2004.09.005

Source DB:  PubMed          Journal:  Prim Care Respir J        ISSN: 1471-4418


  9 in total

Review 1.  The paradox of adult asthma control: "who's in control anyway?".

Authors:  Rick Hodder
Journal:  Can Respir J       Date:  2007 May-Jun       Impact factor: 2.409

Review 2.  What are validated self-report adherence scales really measuring?: a systematic review.

Authors:  Thi-My-Uyen Nguyen; Adam La Caze; Neil Cottrell
Journal:  Br J Clin Pharmacol       Date:  2014-03       Impact factor: 4.335

3.  Volitional nonadherence in pediatric asthma: parental report of motivating factors.

Authors:  Montserrat M Graves; Christina D Adams; Jade A Bender; Stacey Simon; And Jay M Portnoy
Journal:  Curr Allergy Asthma Rep       Date:  2007-11       Impact factor: 4.806

4.  Patient-reported outcome instruments that evaluate adherence behaviours in adults with asthma: a systematic review of measurement properties.

Authors:  Myriam Gagné; Louis-Philippe Boulet; Norma Pérez; Jocelyne Moisan
Journal:  Br J Clin Pharmacol       Date:  2018-06-26       Impact factor: 4.335

Review 5.  Suitability of measures of self-reported medication adherence for routine clinical use: a systematic review.

Authors:  Sara Garfield; Sarah Clifford; Lina Eliasson; Nick Barber; Alan Willson
Journal:  BMC Med Res Methodol       Date:  2011-11-03       Impact factor: 4.615

6.  Development of a PATIENT-Medication Adherence Instrument (P-MAI) and a HEALTHCARE PROFESSIONAL-Medication Adherence Instrument (H-MAI) using the nominal group technique.

Authors:  Sheron Sir Loon Goh; Pauline Siew Mei Lai; Su-May Liew; Kit Mun Tan; Wen Wei Chung; Siew Siang Chua
Journal:  PLoS One       Date:  2020-11-11       Impact factor: 3.240

7.  Patient-reported outcome measures to detect intentional, mixed, or unintentional non-adherence to medication: a systematic review.

Authors:  Mathumalar Loganathan Fahrni; Kamaliah Md Saman; Ali Saleh Alkhoshaiban; Faiza Naimat; Farzan Ramzan; Khairil Anuar Md Isa
Journal:  BMJ Open       Date:  2022-09-19       Impact factor: 3.006

8.  Association between perceived treatment adherence and health-related quality of life in children with juvenile idiopathic arthritis: perspectives of both parents and children.

Authors:  Karine Toupin April; Debbie Ehrmann Feldman; Maria Victoria Zunzunegui; Ciarán M Duffy
Journal:  Patient Prefer Adherence       Date:  2008-02-02       Impact factor: 2.711

9.  Frequency of non-asthma GP visits predicts asthma exacerbations: an observational study in general practice.

Authors:  Michael E Hyland; Ben Whalley; David M G Halpin; Colin J Greaves; Clare Seamark; Sue Blake; Margaret Pinnuck; David Ward; Adam Hawkins; Dave Seamark
Journal:  Prim Care Respir J       Date:  2012-12
  9 in total

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