Literature DB >> 16701144

Strategies for recombinant allergen vaccines and fruitful results from first clinical studies.

Oliver Cromwell1, Helmut Fiebig, Roland Suck, Helga Kahlert, Andreas Nandy, Jens Kettner, Annemie Narkus.   

Abstract

Recombinant DNA technology has delivered the prospect of a new generation of preparations for allergen-specific immunotherapy. The first clinical studies with recombinant allergens have yielded encouraging results, suggesting that there is a good chance that such preparations will become available for use in the routine management of allergic disease.

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Year:  2006        PMID: 16701144     DOI: 10.1016/j.iac.2006.02.001

Source DB:  PubMed          Journal:  Immunol Allergy Clin North Am        ISSN: 0889-8561            Impact factor:   3.479


  4 in total

Review 1.  [Microarray technique for component resolved diagnosis (CRD) in type-I allergies. An innovative technology at the border between research tool and routine diagnostics].

Authors:  L Klimek; D Vetter; L von Bernus; C Thorn
Journal:  HNO       Date:  2011-10       Impact factor: 1.284

2.  [Specific immunotherapy : clinical experience with recombinant molecular major allergens and hypoallergenic variants].

Authors:  P Schendzielorz; L Klimek
Journal:  HNO       Date:  2013-10       Impact factor: 1.284

Review 3.  Virus-like particles (VLP) in prophylaxis and immunotherapy of allergic diseases.

Authors:  Ludger Klimek; Thomas Kündig; Matthias F Kramer; Sonja Guethoff; Erika Jensen-Jarolim; Carsten B Schmidt-Weber; Oskar Palomares; Mona O Mohsen; Thilo Jakob; Martin Bachmann
Journal:  Allergo J Int       Date:  2018-07-09

4.  Allergy immunotherapy with a hypoallergenic recombinant birch pollen allergen rBet v 1-FV in a randomized controlled trial.

Authors:  Ludger Klimek; Claus Bachert; Karl-Friedrich Lukat; Oliver Pfaar; Hanns Meyer; Annemie Narkus
Journal:  Clin Transl Allergy       Date:  2015-08-03       Impact factor: 5.871

  4 in total

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