| Literature DB >> 16699680 |
Marcos Pereira de Avila1, André Moraes Freitas, David Leonardo Cruvinel Isaac, André Luis de Moura Bastos, Rafael Valadares Pena.
Abstract
Interferon is an immunomodulating cytokine used to treat patients with different diseases, such as hepatitis C chronic infection. Pegylated interferon is a new type of interferon, developed to increase the half-life of the drug. Many side effects have been related to its use, including ocular toxicity and retinopathy. The most reported ocular findings are cotton-wool spots and hemorrhages located at the posterior pole and surrounding optic nerve head. We describe one case of pegylated interferon-associated retinopathy with visual loss. The patient had visual acuity improvement four weeks after discontinuation of the medication and the ocular findings became much more subtle.Entities:
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Year: 2006 PMID: 16699680 DOI: 10.1590/s0004-27492006000200022
Source DB: PubMed Journal: Arq Bras Oftalmol ISSN: 0004-2749 Impact factor: 0.872