Literature DB >> 16699445

Vision loss in younger patients: a review of choroidal neovascularization.

David G Miller1, Lawrence J Singerman.   

Abstract

Choroidal neovascularization (CNV) is a common cause of vision loss in patients <50 years of age. In these patients, CNV is often the result of pathologic myopia, ocular histoplasmosis syndrome, angioid streaks, or idiopathic causes. Rarely, CNV is seen in children, usually in association with inherited macular dystrophies such as Best's disease (vitelliform macular dystrophy) or drusen of the optic nerve. This article discusses the role of optometrists in the detection and management of CNV. Untreated CNV can cause rapid deterioration of central vision and is associated with a poor prognosis. Optometrists may be able to improve the prognosis of younger patients with CNV by recognizing the signs, symptoms, and risk factors for CNV and promptly referring patients with suspected CNV to a retina specialist. They can also help patients by providing long-term support and rehabilitation. Recent treatment advances, such as the availability of verteporfin (Visudyne; Novartis Pharma AG, Basel, Switzerland) therapy, that are applicable to younger patients with CNV have increased the importance of early detection of CNV and prompt referral of patients to a specialist who can treat CNV.

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Year:  2006        PMID: 16699445     DOI: 10.1097/01.opx.0000216019.88256.eb

Source DB:  PubMed          Journal:  Optom Vis Sci        ISSN: 1040-5488            Impact factor:   1.973


  13 in total

1.  Relationship between complement membrane attack complex, chemokine (C-C motif) ligand 2 (CCL2) and vascular endothelial growth factor in mouse model of laser-induced choroidal neovascularization.

Authors:  Juan Liu; Purushottam Jha; Valeriy V Lyzogubov; Ruslana G Tytarenko; Nalini S Bora; Puran S Bora
Journal:  J Biol Chem       Date:  2011-04-22       Impact factor: 5.157

2.  [Morphological features of myopic choroidal neovascularization: differences to neovascular age-related macular degeneration].

Authors:  W Inhoffen; F Ziemssen
Journal:  Ophthalmologe       Date:  2012-08       Impact factor: 1.059

3.  Risk of choroidal neovascularization among the uveitides.

Authors:  Sally L Baxter; Maxwell Pistilli; Siddharth S Pujari; Teresa L Liesegang; Eric B Suhler; Jennifer E Thorne; C Stephen Foster; Douglas A Jabs; Grace A Levy-Clarke; Robert B Nussenblatt; James T Rosenbaum; John H Kempen
Journal:  Am J Ophthalmol       Date:  2013-06-21       Impact factor: 5.258

4.  Simultaneous bilateral inflammatory choroidal neovascularization in a case of healed serpiginous-like choroiditis.

Authors:  Gitanjli Sood; Ramanuj Samanta; Devesh Kumawat; Prateek Nishant
Journal:  GMS Ophthalmol Cases       Date:  2022-05-20

5.  Combination therapy for choroidal neovascularisation.

Authors:  Albert J Augustin; Indre Offermann
Journal:  Drugs Aging       Date:  2007       Impact factor: 3.923

6.  OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY OF CHOROIDAL NEOVASCULARIZATION IN FOUR INHERITED RETINAL DYSTROPHIES.

Authors:  Rachel C Patel; Simon S Gao; Miao Zhang; Talal Alabduljalil; Abdullah Al-Qahtani; Richard G Weleber; Paul Yang; Yali Jia; David Huang; Mark E Pennesi
Journal:  Retina       Date:  2016-12       Impact factor: 4.256

7.  An efficacy analysis of anti-vascular endothelial growth factor therapy for choroidal neovascularization secondary to multifocal choroiditis and comparison with wet age-related macular degeneration.

Authors:  Lei Feng; Jiang-Hua Hu; Jie Chen; Xin Xie
Journal:  J Zhejiang Univ Sci B       Date:  2018 Apr.       Impact factor: 3.066

8.  Inflammatory cytokines in aqueous humor of patients with choroidal neovascularization.

Authors:  Heng Miao; Yong Tao; Xiao-xin Li
Journal:  Mol Vis       Date:  2012-03-02       Impact factor: 2.367

9.  Preparation of naringenin/ β-cyclodextrin complex and its more potent alleviative effect on choroidal neovascularization in rats.

Authors:  Xin-rong Xu; Hai-tao Yu; Li Hang; Yan Shao; Shu-hua Ding; Xue-wen Yang
Journal:  Biomed Res Int       Date:  2014-03-27       Impact factor: 3.411

10.  Clinical characteristics and antivascular endothelial growth factor effect of choroidal neovascularization in younger patients in Taiwan.

Authors:  Yi-Hsuan Li; Cheng-Kuo Cheng; Yu-Tang Tseng
Journal:  Taiwan J Ophthalmol       Date:  2015-04-24
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