Literature DB >> 16698232

[Intracerebral haemorrhage, what's new?].

P Grillo1, L Velly, N Bruder.   

Abstract

Haemorrhagic stroke is frequent and associated with a high mortality and morbidity. Less than 30% of patients are still alive five years after onset and few patients regain functional independence. The worsening effect of anticoagulation has been demonstrated and the failure to rapidly normalize coagulation further increases haematoma expansion. In a recent phase II trial, recombinant activated factor VII given within 4 hours of stroke onset, reduced haematoma growth, mortality and disability. An aggressive blood pressure and intracranial pressure control early after the haemorrhage seems beneficial. A large prospective randomized study (the STICH trial) did not demonstrate any beneficial effect of surgery.

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Year:  2006        PMID: 16698232     DOI: 10.1016/j.annfar.2006.03.030

Source DB:  PubMed          Journal:  Ann Fr Anesth Reanim        ISSN: 0750-7658


  1 in total

1.  Severe non-traumatic bleeding events detected by computed tomography: do anticoagulants and antiplatelet agents have a role?

Authors:  Olivier Risch; Agaicha Alfidja; Aurelien Mulliez; Anderson H Amani; Louis Boyer; Lionel Camilleri; Kasra Azarnoush
Journal:  J Cardiothorac Surg       Date:  2014-10-15       Impact factor: 1.637

  1 in total

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