| Literature DB >> 16697974 |
Adele L Boskey1, Michel Goldberg, Ashok Kulkarni, Santiago Gomez.
Abstract
Bone is a complex tissue whose composition and properties vary with age, sex, diet, tissue type, health and disease. In this review, we demonstrate how infrared spectroscopy and infrared spectroscopic imaging can be applied to the study of these variations. A specific example of mice with Fabry disease (a lipid storage disease) is presented in which it is demonstrated that the bones of these young animals, while showing typical spatial variation in mineral content, mineral crystal size, and collagen maturity, do not differ from the bones of age- and sex-matched wild type animals.Entities:
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Year: 2006 PMID： 16697974 PMCID： PMC1551908 DOI： 10.1016/j.bbamem.2006.02.019
Source DB: PubMed Journal: Biochim Biophys Acta ISSN： 0006-3002