| Literature DB >> 16697903 |
Munemitsu Masuda1, Hiroki Sato, Hiroshi Kamata, Tomoe Katsuo, Akiko Takenaka, Ryuichi Miura, Misako Yoneda, Kyoko Tsukiyama-Kohara, Kiyohisa Mizumoto, Chieko Kai.
Abstract
We have established four monoclonal antibodies (MAbs) against the nucleocapsid protein (NP) of canine distemper virus (CDV). A competitive binding assay has revealed that the MAbs are directed against two antigenic domains. An immunofluorescence assay using a series of deletion clones of the NP and an immunoprecipitation assay using the NP have revealed that two of the MAbs recognize the C-terminal region of the NP while the other two recognize the tertiary structure of the N-terminal domain. These MAbs reacted with all eight strains of CDV used in this study, but showed different reactivities against measles virus and rinderpest virus.Entities:
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Year: 2006 PMID： 16697903 DOI： 10.1016/j.cimid.2006.03.004
Source DB: PubMed Journal: Comp Immunol Microbiol Infect Dis ISSN： 0147-9571 Impact factor: 2.268