| Literature DB >> 16697070 |
Abstract
Early studies suggested that proteins with a greater contribution to the fitness of an organism evolve more slowly than less 'important' proteins. Recent articles by two research groups highlight the long-standing controversy about the genome-wide relationships between the measures of evolution rate, protein abundance and the fitness effect of gene disruption. These studies highlight the need for truly multidimensional approaches to the issues of quantitative genomics.Entities:
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Year: 2006 PMID： 16697070 DOI： 10.1016/j.tig.2006.04.009
Source DB: PubMed Journal: Trends Genet ISSN： 0168-9525 Impact factor: 11.639