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Literature DB >> 16691026

Trojan horse meets magic bullet to spawn a novel, highly effective drug delivery model.

Andras G Lacko¹, Maya Nair, Sulabha Paranjape, Linda Mooberry, Walter J McConathy.

Abstract

Because of their physicochemical properties and the selective receptor-mediated uptake of their core components, reconstituted high-density lipoproteins have unique advantages over conventional formulations to serve as targeted drug delivery agents.

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Year: 2006 PMID： 16691026 DOI： 10.1159/000093268

Source DB: PubMed Journal: Chemotherapy ISSN： 0009-3157 Impact factor: 2.544

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Cited

12 in total

1. Validation of the reconstituted high-density lipoprotein (rHDL) drug delivery platform using dilauryl fluorescein (DLF).

Authors: Walter J McConathy; Sulabha Paranjape; Linda Mooberry; Sabitha Buttreddy; Maya Nair; Andras G Lacko
Journal: Drug Deliv Transl Res Date: 2011-04 Impact factor: 4.617

2. Harnessing high density lipoproteins to block transforming growth factor beta and to inhibit the growth of liver tumor metastases.

Authors: José Medina-Echeverz; Jessica Fioravanti; Nancy Díaz-Valdés; Kathrin Frank; Fernando Aranda; Celia Gomar; Nuria Ardaiz; Javier Dotor; Viktor Umansky; Jesús Prieto; Pedro Berraondo
Journal: PLoS One Date: 2014-05-05 Impact factor: 3.240

Review 3. HDL and microRNA therapeutics in cardiovascular disease.

Authors: Danielle L Michell; Kasey C Vickers
Journal: Pharmacol Ther Date: 2016-09-03 Impact factor: 12.310

4. Photophysical characterization of anticancer drug valrubicin in rHDL nanoparticles and its use as an imaging agent.

Authors: Sunil Shah; Rahul Chib; Sangram Raut; Jaclyn Bermudez; Nirupama Sabnis; Divya Duggal; Joseph D Kimball; Andras G Lacko; Zygmunt Gryczynski; Ignacy Gryczynski
Journal: J Photochem Photobiol B Date: 2015-12-18 Impact factor: 6.252

5. Enhanced solubility and functionality of valrubicin (AD-32) against cancer cells upon encapsulation into biocompatible nanoparticles.

Authors: Nirupama Sabnis; Maya Nair; Mervyn Israel; Walter J McConathy; Andras G Lacko
Journal: Int J Nanomedicine Date: 2012-02-22

Review 6. The role of cholesterol metabolism and cholesterol transport in carcinogenesis: a review of scientific findings, relevant to future cancer therapeutics.

Authors: Pedro M R Cruz; Huanbiao Mo; Walter J McConathy; Nirupama Sabnis; Andras G Lacko
Journal: Front Pharmacol Date: 2013-09-25 Impact factor: 5.810

Trojan horse meets magic bullet to spawn a novel, highly effective drug delivery model.

1. Validation of the reconstituted high-density lipoprotein (rHDL) drug delivery platform using dilauryl fluorescein (DLF).

2. Harnessing high density lipoproteins to block transforming growth factor beta and to inhibit the growth of liver tumor metastases.

Review 3. HDL and microRNA therapeutics in cardiovascular disease.

4. Photophysical characterization of anticancer drug valrubicin in rHDL nanoparticles and its use as an imaging agent.

5. Enhanced solubility and functionality of valrubicin (AD-32) against cancer cells upon encapsulation into biocompatible nanoparticles.

Review 6. The role of cholesterol metabolism and cholesterol transport in carcinogenesis: a review of scientific findings, relevant to future cancer therapeutics.

7. High-density lipoprotein contribute to G0-G1/S transition in Swiss NIH/3T3 fibroblasts.

8. The potential role of nanotechnology in therapeutic approaches for triple negative breast cancer.

Review 9. HDL as a drug and nucleic acid delivery vehicle.

10. SR-B1-targeted nanodelivery of anti-cancer agents: a promising new approach to treat triple-negative breast cancer.