Literature DB >> 16690538

An evaluation of the biological and toxicological properties of Aloe barbadensis (miller), Aloe vera.

Mary D Boudreau1, Frederick A Beland.   

Abstract

Aloe barbadensis (Miller), Aloe vera, has a long history of use as a topical and oral therapeutic. The plant is the source of two products, gel and latex, which are obtained from its fleshy leaves. Aloe vera products contain multiple constituents with potential biological and toxicological activities, yet the active components elude definition. Ingestion of Aloe vera is associated with diarrhea, electrolyte imbalance, kidney dysfunction, and conventional drug interactions; episodes of contact dermatitis, erythema, and phototoxicity have been reported from topical applications. This review examines the botany, physical and chemical properties, and biological activities of the Aloe vera plant.

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Year:  2006        PMID: 16690538     DOI: 10.1080/10590500600614303

Source DB:  PubMed          Journal:  J Environ Sci Health C Environ Carcinog Ecotoxicol Rev        ISSN: 1059-0501            Impact factor:   3.781


  66 in total

1.  Aloe vera non-decolorized whole leaf extract-induced large intestinal tumors in F344 rats share similar molecular pathways with human sporadic colorectal tumors.

Authors:  Arun R Pandiri; Robert C Sills; Mark J Hoenerhoff; Shyamal D Peddada; Thai-Vu T Ton; Hue-Hua L Hong; Gordon P Flake; David E Malarkey; Greg R Olson; Igor P Pogribny; Nigel J Walker; Mary D Boudreau
Journal:  Toxicol Pathol       Date:  2011-09-21       Impact factor: 1.902

Review 2.  Roles and mechanisms of stem cell in wound healing.

Authors:  Thurga Ayavoo; Karthikeyan Murugesan; Ashok Gnanasekaran
Journal:  Stem Cell Investig       Date:  2021-03-02

3.  Anticoccidial effects of Aloe secundiflora leaf extract against Eimeria tenella in broiler chicken.

Authors:  Fredrick Kaingu; Dandan Liu; Lele Wang; Jianping Tao; Rebecca Waihenya; Helen Kutima
Journal:  Trop Anim Health Prod       Date:  2017-03-17       Impact factor: 1.559

4.  Mosquitocidal and water purification properties of Cynodon dactylon, Aloe vera, Hemidesmus indicus and Coleus amboinicus leaf extracts against the mosquito vectors.

Authors:  Nareshkumar Arjunan; Kadarkarai Murugan; Pari Madhiyazhagan; Kalimuthu Kovendan; Kanagarajan Prasannakumar; Sundaram Thangamani; Donald R Barnard
Journal:  Parasitol Res       Date:  2011-09-23       Impact factor: 2.289

5.  High prevalence of abscesses and self-treatment among injection drug users in Tijuana, Mexico.

Authors:  Robin A Pollini; Manuel Gallardo; Samreen Hasan; Joshua Minuto; Remedios Lozada; Alicia Vera; María Luisa Zúñiga; Steffanie A Strathdee
Journal:  Int J Infect Dis       Date:  2010-04-08       Impact factor: 3.623

6.  In vitro and in vivo assessment of piroxicam incorporated Aloe vera transgel.

Authors:  Vinesha Velam; Prasanna Raju Yalavarthi; Cr Sundaresan; Kr Vandana; Thushara Bindu Dudala; Haritha Kodavatikanti; Harini Chowdary Vadlamudi
Journal:  Int J Pharm Investig       Date:  2013-10

7.  Treatment-related changes after short-term exposure of SD rats to Aloe vera whole-leaf freeze-dried powder.

Authors:  Tao Chen; Li Wang; Chunyan Hu
Journal:  Int J Exp Pathol       Date:  2017-10       Impact factor: 1.925

8.  Implications for degenerative disorders: antioxidative activity, total phenols, flavonoids, ascorbic acid, beta-carotene and beta-tocopherol in Aloe vera.

Authors:  Nurten Ozsoy; Eda Candoken; Nuriye Akev
Journal:  Oxid Med Cell Longev       Date:  2009 Apr-Jun       Impact factor: 6.543

Review 9.  Traditional Therapies for Skin Wound Healing.

Authors:  Rúben F Pereira; Paulo J Bártolo
Journal:  Adv Wound Care (New Rochelle)       Date:  2016-05-01       Impact factor: 4.730

10.  Clear evidence of carcinogenic activity by a whole-leaf extract of Aloe barbadensis miller (aloe vera) in F344/N rats.

Authors:  Mary D Boudreau; Paul W Mellick; Greg R Olson; Robert P Felton; Brett T Thorn; Frederick A Beland
Journal:  Toxicol Sci       Date:  2012-09-11       Impact factor: 4.849

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