Literature DB >> 16688807

Gastric cancer patients at high-risk of having synchronous cancer.

Jun Ho Lee1, Ja Seong Bae, Keun Won Ryu, Jong Seok Lee, Sook Ryun Park, Chan Gyoo Kim, Myoung Cheorl Kook, Il Ju Choi, Young Woo Kim, Jae-Gahb Park, Jae-Moon Bae.   

Abstract

AIM: To identify patients with a high-risk of having a synchronous cancer among gastric cancer patients.
METHODS: We retrospectively analyzed the prospective gastric cancer database at the National Cancer Center, Korea from December 2000 to December 2004. The clinicopathological characteristics of patients with synchronous cancers and those of patients without synchronous cancers were compared. Multivariate analysis was performed to identify the risk factors for the presence of a synchronous cancer in gastric cancer patients.
RESULTS: 111 of 3291 gastric cancer patients (3.4%) registered in the database had a synchronous cancer. Among these 111 patients, 109 had a single synchronous cancer and 2 patients had two synchronous cancers. The most common form of synchronous cancer was colorectal cancer (42 patients, 37.2%) followed by lung cancer (21 patients, 18.6%). Multivariate analyses revealed that elderly patients with differentiated early gastric cancer have a higher probability of a synchronous cancer.
CONCLUSION: Synchronous cancers in gastric cancer patients are not infrequent. The physicians should try to find synchronous cancers in gastric cancer patients, especially in the elderly with a differentiated early gastric cancer.

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Year:  2006        PMID: 16688807      PMCID: PMC4087994          DOI: 10.3748/wjg.v12.i16.2588

Source DB:  PubMed          Journal:  World J Gastroenterol        ISSN: 1007-9327            Impact factor:   5.742


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