Literature DB >> 16687527

Predictive factors of efficacy of periradicular corticosteroid injections for lumbar radiculopathy.

C Cyteval1, N Fescquet, E Thomas, E Decoux, F Blotman, P Taourel.   

Abstract

BACKGROUND AND
PURPOSE: Steroid periradicular infiltration is a common nonsurgical sciatic pain treatment of inconsistent efficacy. The purpose of this study was to identify factors for predicting the efficacy or failure of this procedure.
METHODS: Two hundred twenty-nine patients with lumbar radiculopathy were prospectively followed up at 2 weeks and 1 year after percutaneous periradicular steroid infiltration. The intensity of radicular pain was scored on the visual analog scale (VAS). Pain relief was classified as "excellent" when the pain was completely resolved or had diminished by 75% or more, "good" for a diminution of 50% to 74%, "fair" for a diminution of 25% to 49%, or "poor" for a diminution of less than 25% or an increase in pain.
RESULTS: The mean VAS scores were 6.5 (range, 3.1-9.5) before and 4.2 (range, 0-9.5) 2 weeks after the procedure. Pain relief was graded as excellent in 45 patients (19.7%), good in 48 patients (21%), fair in 45 patients (19.7%), and poor in 91 patients (39.7%). Cause of pain, conflict location, and pain intensity were not predictive factors of radicular pain relief, whereas the symptom duration before the procedure was highly correlated with the pain relief outcome. Patients with excellent results 2 weeks after the procedure had a mean duration of symptoms of 3.04 months (SD 3.28) versus 7.96 months (DS 9.04) in the group with poor pain relief.
CONCLUSIONS: Periradicular infiltration is a simple, safe, and effective nonsurgical procedure that should be performed quite early in the course of the illness to provide radicular pain relief, because corticosteroid infiltration is less beneficial for patients with more chronic radicular pain.

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Year:  2006        PMID: 16687527      PMCID: PMC7975758     

Source DB:  PubMed          Journal:  AJNR Am J Neuroradiol        ISSN: 0195-6108            Impact factor:   3.825


  31 in total

1.  Corticosteroids inhibit prostaglandin production by rheumatiod synovia.

Authors:  F Kantrowitz; D R Robinson; M B McGuire; L Levine
Journal:  Nature       Date:  1975-12-25       Impact factor: 49.962

2.  The effect of nerve-root injections on the need for operative treatment of lumbar radicular pain. A prospective, randomized, controlled, double-blind study.

Authors:  K D Riew; Y Yin; L Gilula; K H Bridwell; L G Lenke; C Lauryssen; K Goette
Journal:  J Bone Joint Surg Am       Date:  2000-11       Impact factor: 5.284

Review 3.  Back pain and sciatica.

Authors:  J W Frymoyer
Journal:  N Engl J Med       Date:  1988-02-04       Impact factor: 91.245

4.  Periradicular infiltration for sciatica: a randomized controlled trial.

Authors:  J Karppinen; A Malmivaara; M Kurunlahti; E Kyllönen; T Pienimäki; P Nieminen; A Ohinmaa; O Tervonen; H Vanharanta
Journal:  Spine (Phila Pa 1976)       Date:  2001-05-01       Impact factor: 3.468

Review 5.  Epidural steroids.

Authors:  N Bogduk
Journal:  Spine (Phila Pa 1976)       Date:  1995-04-01       Impact factor: 3.468

Review 6.  Pathoanatomy and pathophysiology of nerve root compression.

Authors:  B Rydevik; M D Brown; G Lundborg
Journal:  Spine (Phila Pa 1976)       Date:  1984 Jan-Feb       Impact factor: 3.468

7.  Experimental lumbar spinal stenosis. Analysis of the cortical evoked potentials, microvasculature, and histopathology.

Authors:  R B Delamarter; H H Bohlman; L D Dodge; C Biro
Journal:  J Bone Joint Surg Am       Date:  1990-01       Impact factor: 5.284

8.  Experimental lumbar radiculopathy. Behavioral and histologic changes in a model of radicular pain after spinal nerve root irritation with chromic gut ligatures in the rat.

Authors:  M Kawakami; J N Weinstein; K Chatani; K F Spratt; S T Meller; G F Gebhart
Journal:  Spine (Phila Pa 1976)       Date:  1994-08-15       Impact factor: 3.468

9.  Outpatient lumbar epidural corticosteroid injection in the management of sciatica.

Authors:  M G Ridley; G H Kingsley; T Gibson; R Grahame
Journal:  Br J Rheumatol       Date:  1988-08

10.  The role of steroids and their effects on phospholipase A2. An animal model of radiculopathy.

Authors:  H M Lee; J N Weinstein; S T Meller; N Hayashi; K F Spratt; G F Gebhart
Journal:  Spine (Phila Pa 1976)       Date:  1998-06-01       Impact factor: 3.468

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  14 in total

1.  What types of degenerative lumbar pathologies respond to nerve root injection? A retrospective review of six hundred and forty one cases.

Authors:  Masahiro Kanayama; Fumihiro Oha; Tomoyuki Hashimoto
Journal:  Int Orthop       Date:  2015-04-16       Impact factor: 3.075

Review 2.  Access routes and reported decision criteria for lumbar epidural drug injections: a systematic literature review.

Authors:  Gustav Andreisek; Maja Jenni; Dominic Klingler; Maria Wertli; Marina Elliott; Erika J Ulbrich; Sebastian Winklhofer; Johann Steurer
Journal:  Skeletal Radiol       Date:  2013-08-31       Impact factor: 2.199

3.  CT-guided infiltration saves surgical intervention and fastens return to work compared to anatomical landmark-guided infiltration in patients with lumbosciatica.

Authors:  Moritz C Deml; Michael Buhr; Matthias D Wimmer; Robert Pflugmacher; Rainer Riedel; Yorck Rommelspacher; Koroush Kabir
Journal:  Eur J Orthop Surg Traumatol       Date:  2015-02-24

4.  Pain reduction after lumbar epidural injections using particulate versus non-particulate steroids: intensity of the baseline pain matters.

Authors:  Marek Tagowski; Zbigniew Lewandowski; Jürg Hodler; Thomas Spiegel; Gerhard W Goerres
Journal:  Eur Radiol       Date:  2019-03-18       Impact factor: 5.315

5.  Ultra-low-dose periradicular infiltration of the lumbar spine: spot scanning and its potential for further dose reduction by replacing helical planning CT.

Authors:  Fabian Henry Jürgen Elsholtz; Lars-Arne Schaafs; Christoph Erxleben; Bernd Hamm; Stefan Markus Niehues
Journal:  Radiol Med       Date:  2017-04-20       Impact factor: 3.469

Review 6.  Particulate and non-particulate steroids in spinal epidurals: a systematic review and meta-analysis.

Authors:  I H Feeley; E F Healy; J Noel; P J Kiely; T M Murphy
Journal:  Eur Spine J       Date:  2016-02-12       Impact factor: 3.134

7.  Percutaneous treatment of intervertebral disc herniation.

Authors:  Xavier Buy; Afshin Gangi
Journal:  Semin Intervent Radiol       Date:  2010-06       Impact factor: 1.513

8.  Cervical radiculopathy: study protocol of a randomised clinical trial evaluating the effect of mobilisations and exercises targeting the opening of intervertebral foramen [NCT01500044].

Authors:  Pierre Langevin; Jean-Sébastien Roy; François Desmeules
Journal:  BMC Musculoskelet Disord       Date:  2012-01-31       Impact factor: 2.362

9.  Lumbar Selective Nerve Root Block: Comparative Study Using Two Pharmacological Formulae.

Authors:  Juan Pablo Guyot
Journal:  Global Spine J       Date:  2017-09-01

10.  Predictive factors for treatment success of transforaminal epidural steroid injection in lumbar disc herniation-induced sciatica

Authors:  Savaş Şencan; Alp Eren Çelenlioğlu; Ruslan Asadov; Osman Hakan Gündüz
Journal:  Turk J Med Sci       Date:  2020-02-13       Impact factor: 0.973

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