Literature DB >> 16686593

Strategies for treating chronic insomnia.

Anna K Morin1.   

Abstract

Insomnia is a prevalent condition that remains underdiagnosed and undertreated. Recognizing and treating insomnia are important in decreasing morbidity and restoring quality of life for those who experience sleep disturbances. Appropriate treatment of insomnia should involve multiple interventions designed to address not only the symptoms of insomnia itself, but also any coexisting factors that may be contributing to the sleep disturbances. A combination of pharmacologic and nonpharmacologic therapies may be particularly efficacious in those with chronic and debilitating insomnia. Pharmacotherapy is the most frequently used intervention for insomnia in cases where the goal of therapy is immediate relief of symptoms, insomnia is accompanied by significant distress or impairment, nonpharmacologic approaches alone are ineffective, or the patient prefers medication. The ideal hypnotic has the following characteristics: rapid absorption, rapid sleep induction, optimal duration of action, preservation of sleep architecture, and a favorable safety profile. This review will discuss currently available treatment options for insomnia, the benefits of each, and appropriate treatment regimens.

Entities:  

Mesh:

Year:  2006        PMID: 16686593

Source DB:  PubMed          Journal:  Am J Manag Care        ISSN: 1088-0224            Impact factor:   2.229


  12 in total

1.  Benzodiazepine use in Belgian nursing homes: a closer look into indications and dosages.

Authors:  Jolyce Bourgeois; Monique M Elseviers; Majda Azermai; Luc Van Bortel; Mirko Petrovic; Robert R Vander Stichele
Journal:  Eur J Clin Pharmacol       Date:  2011-12-22       Impact factor: 2.953

2.  Patients with treatment-resistant insomnia taking nightly prescription medications for sleep: a retrospective assessment of diagnostic and treatment variables.

Authors:  Barry Krakow; Victor A Ulibarri; Edward A Romero
Journal:  Prim Care Companion J Clin Psychiatry       Date:  2010

3.  Effects of eszopiclone and zolpidem on sleep-wake behavior, anxiety-like behavior and contextual memory in rats.

Authors:  Max P Huang; Kushan Radadia; Brian W Macone; Sanford H Auerbach; Subimal Datta
Journal:  Behav Brain Res       Date:  2010-02-12       Impact factor: 3.332

4.  Dopamine D1 and D2 receptors mediate analgesic and hypnotic effects of l-tetrahydropalmatine in a mouse neuropathic pain model.

Authors:  Yuan-Yuan Liu; Tian-Xiao Wang; Ji-Chuan Zhou; Wei-Min Qu; Zhi-Li Huang
Journal:  Psychopharmacology (Berl)       Date:  2019-06-06       Impact factor: 4.530

5.  Potentiating effect of eszopiclone on GABA(A) receptor-mediated responses in pedunculopontine neurons.

Authors:  Meijun Ye; Edgar Garcia-Rill
Journal:  Sleep       Date:  2009-07       Impact factor: 5.849

6.  Effects of eszopiclone and zolpidem on sleep and waking states in the adult guinea pig.

Authors:  Mingchu Xi; Michael H Chase
Journal:  Sleep       Date:  2008-07       Impact factor: 5.849

7.  Piromelatine exerts antinociceptive effect via melatonin, opioid, and 5HT1A receptors and hypnotic effect via melatonin receptors in a mouse model of neuropathic pain.

Authors:  Yuan-Yuan Liu; Dou Yin; Li Chen; Wei-Min Qu; Chang-Rui Chen; Moshe Laudon; Neng-Neng Cheng; Yoshihiro Urade; Zhi-Li Huang
Journal:  Psychopharmacology (Berl)       Date:  2014-04-04       Impact factor: 4.530

8.  Quality of life in patients suffering from insomnia.

Authors:  Waguih W Ishak; Kara Bagot; Shannon Thomas; Naira Magakian; Dina Bedwani; David Larson; Alexandra Brownstein; Christine Zaky
Journal:  Innov Clin Neurosci       Date:  2012-10

9.  An approach to long-term sedative-hypnotic use.

Authors:  Azmeh Shahid; Sharon A Chung; Ron Phillipson; Colin M Shapiro
Journal:  Nat Sci Sleep       Date:  2012-04-02

10.  The impact of age on the hypnotic effects of eszopiclone and zolpidem in the guinea pig.

Authors:  Mingchu Xi; Michael H Chase
Journal:  Psychopharmacology (Berl)       Date:  2009-04-03       Impact factor: 4.530

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