Literature DB >> 16684726

Prices, profits, and innovation: examining criticisms of new psychotropic drugs' value.

Haiden A Huskamp1.   

Abstract

High profits and high drug costs have brought increased scrutiny of the pharmaceutical industry over the issue of whether the drugs they produce are worth the costs. I examine several related complaints, including the proliferation of me-too drugs and product reformulations, which some argue have little value relative to their cost; the baseless promotion of newer drug classes as more effective than existing, less expensive drugs; legal strategies to extend market exclusivity that result in high brand-name drug prices for an extended period of time; and large promotional expenditures that result in higher prices.

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Year:  2006        PMID: 16684726      PMCID: PMC2430611          DOI: 10.1377/hlthaff.25.3.635

Source DB:  PubMed          Journal:  Health Aff (Millwood)        ISSN: 0278-2715            Impact factor:   6.301


  22 in total

1.  Choosing a first-line antidepressant: equal on average does not mean equal for everyone.

Authors:  G Simon
Journal:  JAMA       Date:  2001-12-19       Impact factor: 56.272

2.  Direct-to-consumer advertising--strengthening our health care system.

Authors:  Alan F Holmer
Journal:  N Engl J Med       Date:  2002-02-14       Impact factor: 91.245

3.  The impact of direct-to-consumer advertising.

Authors:  Carol Lewis
Journal:  FDA Consum       Date:  2003 Mar-Apr

4.  New estimates of drug development costs.

Authors:  Richard G Frank
Journal:  J Health Econ       Date:  2003-03       Impact factor: 3.883

5.  A meta-analysis of the efficacy of second-generation antipsychotics.

Authors:  John M Davis; Nancy Chen; Ira D Glick
Journal:  Arch Gen Psychiatry       Date:  2003-06

6.  Managing psychotropic drug costs: will formularies work?

Authors:  Haiden A Huskamp
Journal:  Health Aff (Millwood)       Date:  2003 Sep-Oct       Impact factor: 6.301

7.  The choice of antipsychotic drugs for schizophrenia.

Authors:  Robert Freedman
Journal:  N Engl J Med       Date:  2005-09-19       Impact factor: 91.245

8.  Ghost story: at medical journals, writers paid by industry play big role.

Authors:  Anna Wilde Mathews
Journal:  Wall St J (East Ed)       Date:  2005-12-13

9.  Fixed-dose trial of the single isomer SSRI escitalopram in depressed outpatients.

Authors:  William J Burke; Ivan Gergel; Anjana Bose
Journal:  J Clin Psychiatry       Date:  2002-04       Impact factor: 4.384

10.  Risk of death in elderly users of conventional vs. atypical antipsychotic medications.

Authors:  Philip S Wang; Sebastian Schneeweiss; Jerry Avorn; Michael A Fischer; Helen Mogun; Daniel H Solomon; M Alan Brookhart
Journal:  N Engl J Med       Date:  2005-12-01       Impact factor: 91.245

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  8 in total

Review 1.  Pharmacological and psychosocial management of mental, neurological and substance use disorders in low- and middle-income countries: issues and current strategies.

Authors:  Jair de Jesus Mari; Luís Fernando Tófoli; Cristiano Noto; Li M Li; Alessandra Diehl; Angélica M Claudino; Mario F Juruena
Journal:  Drugs       Date:  2013-09       Impact factor: 9.546

Review 2.  Should financial incentives be used to differentially reward 'me-too' and innovative drugs?

Authors:  Brita Pekarsky
Journal:  Pharmacoeconomics       Date:  2010       Impact factor: 4.981

3.  [Scientific evidence and the cost of innovations in the health-care system].

Authors:  Franz Porzsolt; Jonas Schreyögg
Journal:  Med Klin (Munich)       Date:  2009-08-23

4.  Who are the new users of antipsychotic medications?

Authors:  Marisa Elena Domino; Marvin S Swartz
Journal:  Psychiatr Serv       Date:  2008-05       Impact factor: 3.084

5.  What is the value of 'me-too' drugs?

Authors:  Stephane Régnier
Journal:  Health Care Manag Sci       Date:  2013-02-26

Review 6.  Comparative efficacy and risk of harms of immediate- versus extended-release second-generation antidepressants: a systematic review with network meta-analysis.

Authors:  Barbara Nussbaumer; Laura C Morgan; Ursula Reichenpfader; Amy Greenblatt; Richard A Hansen; Megan Van Noord; Linda Lux; Bradley N Gaynes; Gerald Gartlehner
Journal:  CNS Drugs       Date:  2014-08       Impact factor: 5.749

7.  Racial and ethnic disparities in the treatment of a Medicaid population with schizophrenia.

Authors:  Marcela Horvitz-Lennon; Thomas G McGuire; Margarita Alegria; Richard G Frank
Journal:  Health Serv Res       Date:  2009-09-24       Impact factor: 3.402

8.  Medicare inpatient treatment for elderly non-dementia psychiatric illnesses 1992--2002; length of stay and expenditures by facility type.

Authors:  Donald R Hoover; Ayse Akincigil; Jonathan D Prince; Ece Kalay; Judith A Lucas; James T Walkup; Stephen Crystal
Journal:  Adm Policy Ment Health       Date:  2008-02-22
  8 in total

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