Literature DB >> 1668304

Sialic acid activation.

E L Kean1.   

Abstract

Cytidine 5'-monophosphosialic acid (CMP-sialic acid) is the activated form of sialic acid which is required for the biosynthesis of sialic acid-containing complex carbohydrates. Its discovery over 30 years ago by the laboratory of Dr Saul Roseman was a landmark in research dealing with the biosynthesis of these compounds. A review is presented of the salient features concerning this molecule: its discovery, chemistry, biosynthesis, subcellular location, enzymatic cleavage, transport and molecular biology. This report does not deal with its utilization by the sialyltransferases.

Entities:  

Mesh：

Substances：

Year:  1991        PMID： 1668304     DOI： 10.1093/glycob/1.5.441

Source DB:  PubMed          Journal:  Glycobiology        ISSN： 0959-6658            Impact factor:   4.313


  17 in total

1.  A ganglioside-specific sialyltransferase localizes to axons and non-Golgi structures in neurons.

Authors:  C A Stern; M Tiemeyer
Journal:  J Neurosci       Date:  2001-03-01       Impact factor: 6.167

2.  Biochemical engineering of cell surface sialic acids stimulates axonal growth.

Authors:  Bettina Büttner; Christoph Kannicht; Carolin Schmidt; Klemens Löster; Werner Reutter; Hye-Youn Lee; Sabine Nöhring; Rüdiger Horstkorte
Journal:  J Neurosci       Date:  2002-10-15       Impact factor: 6.167

3.  Expression cloning of the Golgi CMP-sialic acid transporter.

Authors:  M Eckhardt; M Mühlenhoff; A Bethe; R Gerardy-Schahn
Journal:  Proc Natl Acad Sci U S A       Date:  1996-07-23       Impact factor: 11.205

Review 4.  Glycoproteins from insect cells: sialylated or not?

Authors:  I Marchal; D L Jarvis; R Cacan; A Verbert
Journal:  Biol Chem       Date:  2001-02       Impact factor: 3.915

5.  An N-linked glycoprotein with alpha(2,3)-linked sialic acid is a receptor for BK virus.

Authors:  Aisling S Dugan; Sylvia Eash; Walter J Atwood
Journal:  J Virol       Date:  2005-11       Impact factor: 5.103

6.  Covalent modification of Lys19 in the CTP binding site of cytidine 5'-monophosphate N-acetylneuraminic acid synthetase.

Authors:  M V Tullius; W F Vann; B W Gibson
Journal:  Protein Sci       Date:  1999-03       Impact factor: 6.725

7.  The role of CMP-N-acetylneuraminic acid hydroxylase in determining the level of N-glycolylneuraminic acid in porcine tissues.

Authors:  Y N Malykh; L Shaw; R Schauer
Journal:  Glycoconj J       Date:  1998-09       Impact factor: 2.916

8.  Characterization of CMP-N-acetylneuraminic acid synthetase of group B streptococci.

Authors:  R F Haft; M R Wessels
Journal:  J Bacteriol       Date:  1994-12       Impact factor: 3.490

9.  Cloning and expression of human sialic acid pathway genes to generate CMP-sialic acids in insect cells.

Authors:  S M Lawrence; K A Huddleston; N Tomiya; N Nguyen; Y C Lee; W F Vann; T A Coleman; M J Betenbaugh
Journal:  Glycoconj J       Date:  2001-03       Impact factor: 2.916

10.  Mammalian cytidine 5'-monophosphate N-acetylneuraminic acid synthetase: a nuclear protein with evolutionarily conserved structural motifs.

Authors:  A K Münster; M Eckhardt; B Potvin; M Mühlenhoff; P Stanley; R Gerardy-Schahn
Journal:  Proc Natl Acad Sci U S A       Date:  1998-08-04       Impact factor: 11.205
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.