Literature DB >> 1668253

Synthesis and 5-HT receptors binding studies of some 3-substituted-2-(4-methyl-1-piperazinyl)-4-phenylquinolines.

M Anzini1, A Cappelli, S Vomero, G Campiani, A Cagnotto, M Skorupska.   

Abstract

The syntheses of some 3-substituted-2-(4-methyl-1-piperazinyl)-4-phenylquinolines are reported. The title compounds were tested for their potential activities on 5-HT receptor subtypes and 5-HT uptake site; compounds 4b-d showed micromolar affinity for 5-HT3 and 5-HT uptake site.

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Year:  1991        PMID: 1668253

Source DB:  PubMed          Journal:  Farmaco        ISSN: 0014-827X


  1 in total

1.  Ethyl 2,6-dichloro-4-phenyl-quinoline-3-carboxyl-ate.

Authors:  S Mohana Roopan; F Nawaz Khan; M Vijetha; Venkatesha R Hathwar; Seik Weng Ng
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2009-11-04
  1 in total

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