| Literature DB >> 16682014 |
Wei Cao1, Xiao-Qiang Li, Li Liu, Minchang Wang, Hui-Ting Fan, Chen Li, Zhengguang Lv, Xiaojing Wang, Qibing Mei.
Abstract
Two water-soluble glucans (designated APS-1cI and APS-1cII) were extracted from the roots of Angelica sinensis (Oliv.) Diels and further purified by anion-exchange and gel-filtration chromatography. Their molecular weights were determined to be 1.7 x 10(5) and 3.9 x 10(4)Da, respectively. The structures of the purified glucans were investigated by a combination of chemical and instrumental analysis, such as methylation analysis, periodate oxidation, GC-MS, as well as FTIR and NMR spectroscopy ((1)H, (13)C, H-H COSY, HSQC, HMBC, TOCSY and NOESY). The data obtained indicated that APS-1cI was a linear alpha-glucan composed of only (1-->6)-alpha-D-Glcp, and APS-1cII had a repeating unit consisting of (1-->4)-alpha-D-Glcp and (1-->6)-alpha-D-Glcp in a molar ratio of 4:1. Such glucans isolated from A. sinensis (Oliv.) Diels have not been previously reported.Entities:
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Year: 2006 PMID： 16682014 DOI： 10.1016/j.carres.2006.04.017
Source DB: PubMed Journal: Carbohydr Res ISSN： 0008-6215 Impact factor: 2.104