Literature DB >> 1668191

Signal transduction pathways controlling multicellular development in Dictyostelium.

R A Firtel1.   

Abstract

The importance of signal transduction pathways in regulating developmental processes in a number of organisms has become evident in recent years. This is exceptionally clear for Dictyostelium, which uses soluble factors to regulate morphogenesis and cellular differentiation. It is now known that many of these processes are controlled by signal transduction pathways mediated by cyclic AMP through cell surface receptors coupled to G proteins, and that others are mediated by the morphogen DIF.

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Year:  1991        PMID: 1668191     DOI: 10.1016/0168-9525(91)90260-w

Source DB:  PubMed          Journal:  Trends Genet        ISSN: 0168-9525            Impact factor:   11.639


  23 in total

1.  DdPK3, which plays essential roles during Dictyostelium development, encodes the catalytic subunit of cAMP-dependent protein kinase.

Authors:  S K Mann; W M Yonemoto; S S Taylor; R A Firtel
Journal:  Proc Natl Acad Sci U S A       Date:  1992-11-15       Impact factor: 11.205

Review 2.  Genetic networks that regulate development in Dictyostelium cells.

Authors:  W F Loomis
Journal:  Microbiol Rev       Date:  1996-03

3.  Antagonistic effects of signal transduction by intracellular and extracellular cAMP on gene regulation in Dictyostelium.

Authors:  I Endl; A Konzok; W Nellen
Journal:  Mol Biol Cell       Date:  1996-01       Impact factor: 4.138

4.  Differential developmental expression of the rep B and rep D xeroderma pigmentosum related DNA helicase genes from Dictyostelium discoideum.

Authors:  S K Lee; S L Yu; M X Garcia; H Alexander; S Alexander
Journal:  Nucleic Acids Res       Date:  1997-06-15       Impact factor: 16.971

5.  Molecular cloning of a cDNA coding for GTP cyclohydrolase I from Dictyostelium discoideum.

Authors:  K Witter; D J Cahill; T Werner; I Ziegler; W Rödl; A Bacher; M Gütlich
Journal:  Biochem J       Date:  1996-10-01       Impact factor: 3.857

Review 6.  Role of PKA in the timing of developmental events in Dictyostelium cells.

Authors:  W F Loomis
Journal:  Microbiol Mol Biol Rev       Date:  1998-09       Impact factor: 11.056

7.  Spatial and temporal expression of the Dictyostelium discoideum G alpha protein subunit G alpha 2: expression of a dominant negative protein inhibits proper prestalk to stalk differentiation.

Authors:  F Carrel; S Dharmawardhane; A M Clark; J A Powell-Coffman; R A Firtel
Journal:  Mol Biol Cell       Date:  1994-01       Impact factor: 4.138

8.  Identification and characterization of multiple A/T-rich cis-acting elements that control expression from Dictyostelium actin promoters: the Dictyostelium actin upstream activating sequence confers growth phase expression and has enhancer-like properties.

Authors:  R Hori; R A Firtel
Journal:  Nucleic Acids Res       Date:  1994-11-25       Impact factor: 16.971

9.  Amino acid substitutions in the Dictyostelium G alpha subunit G alpha 2 produce dominant negative phenotypes and inhibit the activation of adenylyl cyclase, guanylyl cyclase, and phospholipase C.

Authors:  K Okaichi; A B Cubitt; G S Pitt; R A Firtel
Journal:  Mol Biol Cell       Date:  1992-07       Impact factor: 4.138

10.  Effects of inositol starvation on the levels of inositol phosphates and inositol lipids in Neurospora crassa.

Authors:  P L Lakin-Thomas
Journal:  Biochem J       Date:  1993-06-15       Impact factor: 3.857

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