Literature DB >> 1668190

Cross-coupling of signal transduction pathways: zinc finger meets leucine zipper.

R Schüle1, R M Evans.   

Abstract

Cell proliferation and cellular differentiation are often thought of as opposing phenomena. The molecular mechanisms by which steroid, retinoid and thyroid hormones inhibit cellular proliferation and by which growth factors stimulate this process are poorly understood. We discuss recent evidence suggesting that these two signal transduction pathways converge through a process referred to as 'cross-coupling', which involves a possible interaction between steroid hormone receptors and the c-Jun oncoprotein.

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Year:  1991        PMID： 1668190     DOI： 10.1016/0168-9525(91)90259-s

Source DB:  PubMed          Journal:  Trends Genet        ISSN： 0168-9525            Impact factor:   11.639


  50 in total

1.  Functional erythroid promoters created by interaction of the transcription factor GATA-1 with CACCC and AP-1/NFE-2 elements.

Authors:  M Walters; D I Martin
Journal:  Proc Natl Acad Sci U S A       Date:  1992-11-01       Impact factor: 11.205

2.  Antidiabetic thiazolidinediones inhibit leptin (ob) gene expression in 3T3-L1 adipocytes.

Authors:  C B Kallen; M A Lazar
Journal:  Proc Natl Acad Sci U S A       Date:  1996-06-11       Impact factor: 11.205

3.  Zygote formation in the homothallic green alga Chlamydomonas monoica Strehlow.

Authors:  H van den Ende; M L van den Briel; R Lingeman; P van der Gulik; T Munnik
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4.  Manidipine regulates the transcription of cytokine genes.

Authors:  M Roth; R Keul; L R Emmons; W H Hörl; L H Block
Journal:  Proc Natl Acad Sci U S A       Date:  1992-05-01       Impact factor: 11.205

5.  Transcriptional control in keratinocytes and fibroblasts using synthetic ligands.

Authors:  R A Freiberg; S N Ho; P A Khavari
Journal:  J Clin Invest       Date:  1997-06-01       Impact factor: 14.808

6.  A novel genetic system to isolate a dominant negative effector on DNA-binding activity of Oct-2.

Authors:  A Terunuma; K Shiba; T Noda
Journal:  Nucleic Acids Res       Date:  1997-05-15       Impact factor: 16.971

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Authors:  Saja Almarshad
Journal:  Saudi Pharm J       Date:  2014-06-17       Impact factor: 4.330

8.  Ligand modulates the conversion of DNA-bound vitamin D3 receptor (VDR) homodimers into VDR-retinoid X receptor heterodimers.

Authors:  B Cheskis; L P Freedman
Journal:  Mol Cell Biol       Date:  1994-05       Impact factor: 4.272

9.  The nuclear hormone receptor coactivator SRC-1 is a specific target of p300.

Authors:  T P Yao; G Ku; N Zhou; R Scully; D M Livingston
Journal:  Proc Natl Acad Sci U S A       Date:  1996-10-01       Impact factor: 11.205

10.  Mapping of a yeast G protein betagamma signaling interaction.

Authors:  S J Dowell; A L Bishop; S L Dyos; A J Brown; M S Whiteway
Journal:  Genetics       Date:  1998-12       Impact factor: 4.562
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