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Literature DB >> 1668080

Oncoproteins encoded by the cancer-associated human papillomaviruses target the products of the retinoblastoma and p53 tumor suppressor genes.

P M Howley¹, M Scheffner, J Huibregtse, K Münger.

Abstract

Entities: Disease Gene Species

Mesh：

Substances：

Year: 1991 PMID： 1668080 DOI： 10.1101/sqb.1991.056.01.019

Source DB: PubMed Journal: Cold Spring Harb Symp Quant Biol ISSN： 0091-7451

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11 in total

Review 1. Human papillomavirus and skin cancer.

Authors: J M McGregor; M H Rustin
Journal: Postgrad Med J Date: 1994-10 Impact factor: 2.401

2. The human papillomavirus type 16 E6 oncoprotein can down-regulate p53 activity by targeting the transcriptional coactivator CBP/p300.

Authors: H Zimmermann; R Degenkolbe; H U Bernard; M J O'Connor
Journal: J Virol Date: 1999-08 Impact factor: 5.103

3. Inhibition of human papilloma virus E2 DNA binding protein by covalently linked polyamides.

Authors: Thomas D Schaal; William G Mallet; Dustin L McMinn; Nam V Nguyen; Michelle M Sopko; Sam John; Bhavin S Parekh
Journal: Nucleic Acids Res Date: 2003-02-15 Impact factor: 16.971

4. A family of proteins structurally and functionally related to the E6-AP ubiquitin-protein ligase.

Authors: J M Huibregtse; M Scheffner; S Beaudenon; P M Howley
Journal: Proc Natl Acad Sci U S A Date: 1995-03-28 Impact factor: 11.205

5. Reversible repression of papillomavirus oncogene expression in cervical carcinoma cells: consequences for the phenotype and E6-p53 and E7-pRB interactions.

Authors: M von Knebel Doeberitz; C Rittmüller; F Aengeneyndt; P Jansen-Dürr; D Spitkovsky
Journal: J Virol Date: 1994-05 Impact factor: 5.103

6. Somatic mutations affect key pathways in lung adenocarcinoma.

Authors: Li Ding; Gad Getz; David A Wheeler; Elaine R Mardis; Michael D McLellan; Kristian Cibulskis; Carrie Sougnez; Heidi Greulich; Donna M Muzny; Margaret B Morgan; Lucinda Fulton; Robert S Fulton; Qunyuan Zhang; Michael C Wendl; Michael S Lawrence; David E Larson; Ken Chen; David J Dooling; Aniko Sabo; Alicia C Hawes; Hua Shen; Shalini N Jhangiani; Lora R Lewis; Otis Hall; Yiming Zhu; Tittu Mathew; Yanru Ren; Jiqiang Yao; Steven E Scherer; Kerstin Clerc; Ginger A Metcalf; Brian Ng; Aleksandar Milosavljevic; Manuel L Gonzalez-Garay; John R Osborne; Rick Meyer; Xiaoqi Shi; Yuzhu Tang; Daniel C Koboldt; Ling Lin; Rachel Abbott; Tracie L Miner; Craig Pohl; Ginger Fewell; Carrie Haipek; Heather Schmidt; Brian H Dunford-Shore; Aldi Kraja; Seth D Crosby; Christopher S Sawyer; Tammi Vickery; Sacha Sander; Jody Robinson; Wendy Winckler; Jennifer Baldwin; Lucian R Chirieac; Amit Dutt; Tim Fennell; Megan Hanna; Bruce E Johnson; Robert C Onofrio; Roman K Thomas; Giovanni Tonon; Barbara A Weir; Xiaojun Zhao; Liuda Ziaugra; Michael C Zody; Thomas Giordano; Mark B Orringer; Jack A Roth; Margaret R Spitz; Ignacio I Wistuba; Bradley Ozenberger; Peter J Good; Andrew C Chang; David G Beer; Mark A Watson; Marc Ladanyi; Stephen Broderick; Akihiko Yoshizawa; William D Travis; William Pao; Michael A Province; George M Weinstock; Harold E Varmus; Stacey B Gabriel; Eric S Lander; Richard A Gibbs; Matthew Meyerson; Richard K Wilson
Journal: Nature Date: 2008-10-23 Impact factor: 49.962

Oncoproteins encoded by the cancer-associated human papillomaviruses target the products of the retinoblastoma and p53 tumor suppressor genes.

Review 1. Human papillomavirus and skin cancer.

2. The human papillomavirus type 16 E6 oncoprotein can down-regulate p53 activity by targeting the transcriptional coactivator CBP/p300.

3. Inhibition of human papilloma virus E2 DNA binding protein by covalently linked polyamides.

4. A family of proteins structurally and functionally related to the E6-AP ubiquitin-protein ligase.

5. Reversible repression of papillomavirus oncogene expression in cervical carcinoma cells: consequences for the phenotype and E6-p53 and E7-pRB interactions.

6. Somatic mutations affect key pathways in lung adenocarcinoma.

7. The RB tumor suppressor positively regulates transcription of the anti-angiogenic protein NOL7.

Review 8. Epigenetics of cervical cancer. An overview and therapeutic perspectives.

9. Glycogen synthase kinase 3β and cyclin D1 expression in cervical carcinogenesis.

10. The possible role of cell cycle regulators in multistep process of HPV-associated cervical carcinoma.