Literature DB >> 16679795

Patent blue: a novel vital dye in vitreoretinal surgery.

Stefan Mennel1, Carsten H Meyer, Andreas Tietjen, Eduardo B Rodrigues, Jörg C Schmidt.   

Abstract

PURPOSE: To determine a novel vital dye (patent blue; Blueron) for vitreoretinal surgery in a prospective consecutive case series.
METHODS: Five patients with either idiopathic epiretinal membrane (ERM; n = 2), proliferative vitreoretinopathy (n = 2), or a macular hole (n = 1) underwent a three-port pars plana vitrectomy. Patent blue assisted staining of the retinal surface followed by a consecutive peeling of the ERM (n = 4) or of the internal limiting membrane (ILM; n = 1) was performed. The main outcome measures were quality of intraoperative visualization of preretinal structures and postoperative visual acuity.
RESULTS: The dye induced a moderate staining (++) of the ERM and a mild staining (+) of the ILM. Complete ERM and ILM removal was successfully achieved in all cases. A mean visual improvement of three Snellen lines was observed 6 months postoperatively. No visual field defects or visible retinal pigment epithelial changes were present 6 months postoperatively.
CONCLUSION: Patent blue, a novel dye for intraocular applications, may be added as an alternative dye in chromovitrectomy.

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Year:  2006        PMID: 16679795     DOI: 10.1159/000091764

Source DB:  PubMed          Journal:  Ophthalmologica        ISSN: 0030-3755            Impact factor:   3.250


  5 in total

1.  Investigation of the retinal biocompatibility of acid violet for chromovitrectomy.

Authors:  Emmerson Badaró Cardoso; Milton Moraes-Filho; Eduardo B Rodrigues; Mauricio Maia; Fernando M Penha; Eduardo Amorim Novais; Rodrigo A Souza-Lima; Carsten H Meyer; Michel Eid Farah
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2013-01-18       Impact factor: 3.117

Review 2.  Chromovitrectomy: update.

Authors:  Ali M Al-Halafi
Journal:  Saudi J Ophthalmol       Date:  2013-10-17

Review 3.  Complications of Macular Peeling.

Authors:  Mónica Asencio-Duran; Beatriz Manzano-Muñoz; José Luis Vallejo-García; Jesús García-Martínez
Journal:  J Ophthalmol       Date:  2015-09-03       Impact factor: 1.909

4.  Retinal biocompatibility of brilliant blue g with deuterated water for chromovitrectomy.

Authors:  Emmerson Badaró; Milton Moraes-Filho; Mauricio Maia; Fernando M Penha; Eduardo Amorim Novais; Rodrigo A Souza-Lima; Flavio Hirai; Carsten H Meyer; Michel Eid Farah; Eduardo B Rodrigues
Journal:  J Ophthalmic Vis Res       Date:  2014-04

5.  Investigation of new dyes for chromovitrectomy: preclinical biocompatibility of trisodium, orangell and methyl violet.

Authors:  Emmerson Badaro; Rodrigo A Souza-Lima; Eduardo A Novais; Mauricio Maia; Flávio Hirai; Carsten H Meyer; Michel Eid Farah; Eduardo B Rodrigues
Journal:  Int J Retina Vitreous       Date:  2015-04-15
  5 in total

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