Literature DB >> 16679288

Fat breakdown: a function for CGI-58 (ABHD5) provides a new piece of the puzzle.

Chi-Liang Eric Yen1, Robert V Farese.   

Abstract

The hydrolysis of fat stored in adipose tissues is crucial for providing energy during fasting and exercise, and dysregulation of fat breakdown may contribute to metabolic disease. In this issue of Cell Metabolism, report that CGI-58/ABHD5, a lipid-droplet-associated protein that is mutated in a rare disease characterized by excess lipid storage, activates adipose triglyceride lipase and thus may regulate fat mobilization.

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Year:  2006        PMID: 16679288     DOI: 10.1016/j.cmet.2006.04.001

Source DB:  PubMed          Journal:  Cell Metab        ISSN: 1550-4131            Impact factor:   27.287


  5 in total

Review 1.  CGI-58: Versatile Regulator of Intracellular Lipid Droplet Homeostasis.

Authors:  Liqing Yu; Yi Li; Alison Grisé; Huan Wang
Journal:  Adv Exp Med Biol       Date:  2020       Impact factor: 2.622

2.  Endogenous and Synthetic ABHD5 Ligands Regulate ABHD5-Perilipin Interactions and Lipolysis in Fat and Muscle.

Authors:  Matthew A Sanders; Franck Madoux; Ljiljana Mladenovic; Huamei Zhang; Xiangqun Ye; Michelle Angrish; Emilio P Mottillo; Joseph A Caruso; Geoff Halvorsen; William R Roush; Peter Chase; Peter Hodder; James G Granneman
Journal:  Cell Metab       Date:  2015-09-24       Impact factor: 27.287

3.  ATGL/CGI-58-Dependent Hydrolysis of a Lipid Storage Pool in Murine Enterocytes.

Authors:  Melanie Korbelius; Nemanja Vujic; Vinay Sachdev; Sascha Obrowsky; Silvia Rainer; Benjamin Gottschalk; Wolfgang F Graier; Dagmar Kratky
Journal:  Cell Rep       Date:  2019-08-13       Impact factor: 9.423

4.  Vanillic Acid Improves Comorbidity of Cancer and Obesity through STAT3 Regulation in High-Fat-Diet-Induced Obese and B16BL6 Melanoma-Injected Mice.

Authors:  Jinbong Park; Seon Yeon Cho; JongWook Kang; Woo Yong Park; Sujin Lee; Yunu Jung; Min-Woo Kang; Hyun Jeong Kwak; Jae-Young Um
Journal:  Biomolecules       Date:  2020-07-24

5.  Adipose Lipolysis Regulates Cardiac Glucose Uptake and Function in Mice under Cold Stress.

Authors:  Youngshim Choi; Hyunsu Shin; Ziwei Tang; Yute Yeh; Yinyan Ma; Anil K G Kadegowda; Huan Wang; Long Jiang; Rakesh K Arya; Ling Chen; Bingzhong Xue; Hang Shi; Oksana Gavrilova; Liqing Yu
Journal:  Int J Mol Sci       Date:  2021-12-12       Impact factor: 5.923

  5 in total

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