Literature DB >> 16678746

The role of botulinum toxin A in augmentation of the effect of recession and/or resection surgery.

Seyhan B Ozkan1, Aziz Topaloğlu, Sayime Aydin.   

Abstract

PURPOSE: The aim of this study is to assess the effectiveness of intraoperative botulinum toxin A (BTA) injection as an adjunct to the surgical treatment of large-angle esotropia or exotropia.
METHODS: Ten patients were included in the study. Mean age of the patients was 27+/-20 years. Of these 10 patients, 7 were esotropic and 3 exotropic. The average preoperative esodeviation was 73.6+/-16.5 prism diopters and exodeviation was 76.7+/-5.8 PD. Five units of BTA were injected intraoperatively into one of the recessed horizontal rectus muscles in all of the patients.
RESULTS: The average follow-up was 14+/-10 months (range, 8 to 40 months). The average final deviation in the esotropia group was 13+/-9.6 PD of esotropia. The average final deviation in the exotropia group was 4.7+/-5 PD of exotropia. The final deviation of the 70% patients was within 10 PD of esotropia or exotropia.
CONCLUSION: The results of this study suggest that the combination of BTA injection with recession may increase the expected correction of a conventional horizontal rectus muscle surgery.

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Year:  2006        PMID: 16678746     DOI: 10.1016/j.jaapos.2005.11.011

Source DB:  PubMed          Journal:  J AAPOS        ISSN: 1091-8531            Impact factor:   1.220


  10 in total

1.  Tonic pupil after botulinum toxin-A injection for treatment of esotropia in children.

Authors:  Stephen P Christiansen; Danielle L Chandler; Katherine A Lee; Rosanne Superstein; Alejandra de Alba Campomanes; Erick D Bothun; Julie Morin; David K Wallace; Raymond T Kraker
Journal:  J AAPOS       Date:  2016-02       Impact factor: 1.220

2.  The effect of botulinum toxin injection on the hang-back recession of rectus muscles.

Authors:  Young-Woo Suh; Jin-Hwan Park; Yoonae Ann Cho
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2011-01-21       Impact factor: 3.117

3.  Botulinum toxin augmented bilateral lateral rectus recession versus three muscles surgery in large-angle intermittent exotropia.

Authors:  Hala Kamal Mattout; Sameh Mosaad Fouda; Wael M El-Haig
Journal:  Int J Ophthalmol       Date:  2022-10-18       Impact factor: 1.645

Review 4.  Botulinum toxin for the treatment of strabismus.

Authors:  Fiona J Rowe; Carmel P Noonan
Journal:  Cochrane Database Syst Rev       Date:  2017-03-02

5.  Outcomes and Dose-Response Ratio of Surgery on Three Muscles in Large-Angle Exotropia.

Authors:  Reza Nabie; Vahideh Manouchehri; Parinaz Lesan
Journal:  J Curr Ophthalmol       Date:  2021-03-26

6.  Surgery with intraoperative botulinum toxin-A injection for the treatment of large-angle horizontal strabismus: a pilot study.

Authors:  Nilza Minguini; Keila M M de Carvalho; Fábio L S Bosso; Fábio Endo Hirata; Newton Kara-José
Journal:  Clinics (Sao Paulo)       Date:  2012       Impact factor: 2.365

7.  Recession-resection surgery augmented with botulinum toxin a chemodenervation for paralytic horizontal strabismus.

Authors:  Eun-Ji Kim; Samin Hong; Jong Bok Lee; Sueng-Han Han
Journal:  Korean J Ophthalmol       Date:  2012-01-14

8.  Presence of fusion in albinism after strabismus surgery augmented with botulinum toxin (type a) injection.

Authors:  Sepideh Tavakolizadeh; Azadeh Farahi
Journal:  Korean J Ophthalmol       Date:  2013-07-23

9.  Botulinum Toxin Injection with Conjunctival Microincision for the Treatment of Acute Acquired Comitant Esotropia and Its Effectiveness.

Authors:  Hongjia Xu; Weifeng Sun; Shuying Dai; Yanyan Cheng; Jing Zhao; Yuan Liu; Juan Wang; Ya'nan Wang; Yu Gao; Huifang Han; Aijun Han
Journal:  J Ophthalmol       Date:  2020-12-31       Impact factor: 1.909

10.  Supramaximal Recession and Resection Surgery in Large-Angle Strabismus: Outcomes of Large Interventional Case Series Exotropia and Esotropia.

Authors:  Mohammad Reza Talebnejad; Mohammad Karim Johari; Mohammad Reza Khalili; Mousa Zare
Journal:  J Curr Ophthalmol       Date:  2020-03-23
  10 in total

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