Literature DB >> 16678090

New "hogs" in Hedgehog transport and signal reception.

Christopher W Wilson1, Pao-Tien Chuang.   

Abstract

A recent paper in Cell (Yao et al., 2006) and two papers in Developmental Cell (Tenzen et al., 2006; Zhang et al., 2006) identify a new receptor component for Hedgehog, a key morphogen in embryonic development. Many other proteins that bind to Hedgehog in the extracellular matrix or on the cell surface have been identified. In light of these recent discoveries, we discuss how these factors control the stability, transport, reception, and availability of Hedgehog in modulating Hedgehog-mediated responses.

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Year:  2006        PMID: 16678090     DOI: 10.1016/j.cell.2006.04.016

Source DB:  PubMed          Journal:  Cell        ISSN: 0092-8674            Impact factor:   41.582


  11 in total

1.  The cell-surface proteins Dally-like and Ihog differentially regulate Hedgehog signaling strength and range during development.

Authors:  Dong Yan; Yihui Wu; Yongfei Yang; Tatyana Y Belenkaya; Xiaofang Tang; Xinhua Lin
Journal:  Development       Date:  2010-06       Impact factor: 6.868

Review 2.  Dynamic signaling for neural stem cell fate determination.

Authors:  Shu Wen; Hong Li; Jia Liu
Journal:  Cell Adh Migr       Date:  2009-01-10       Impact factor: 3.405

Review 3.  Shaping morphogen gradients by proteoglycans.

Authors:  Dong Yan; Xinhua Lin
Journal:  Cold Spring Harb Perspect Biol       Date:  2009-09       Impact factor: 10.005

Review 4.  My approach to reporting a gastric biopsy.

Authors:  Carlos A Rubio
Journal:  J Clin Pathol       Date:  2006-09-08       Impact factor: 3.411

5.  Brother of cdo (umleitung) is cell-autonomously required for Hedgehog-mediated ventral CNS patterning in the zebrafish.

Authors:  Sadie A Bergeron; Oksana V Tyurina; Emily Miller; Andrea Bagas; Rolf O Karlstrom
Journal:  Development       Date:  2010-11-29       Impact factor: 6.868

Review 6.  Interactions between Hedgehog proteins and their binding partners come into view.

Authors:  Philip A Beachy; Sarah G Hymowitz; Robert A Lazarus; Daniel J Leahy; Christian Siebold
Journal:  Genes Dev       Date:  2010-09-15       Impact factor: 11.361

7.  Structural insights into hedgehog ligand sequestration by the human hedgehog-interacting protein HHIP.

Authors:  Benjamin Bishop; A Radu Aricescu; Karl Harlos; Chris A O'Callaghan; E Yvonne Jones; Christian Siebold
Journal:  Nat Struct Mol Biol       Date:  2009-06-28       Impact factor: 15.369

8.  The use of hedgehog antagonists in cancer therapy: a comparison of clinical outcomes and gene expression analyses.

Authors:  Burthia E Booker; Adam D Steg; Stefan Kovac; Charles N Landen; Hope M Amm
Journal:  Cancer Biol Ther       Date:  2020-09-11       Impact factor: 4.742

9.  Kinetic and structural studies on interactions between heparin or heparan sulfate and proteins of the hedgehog signaling pathway.

Authors:  Fuming Zhang; Jason S McLellan; Alondra M Ayala; Daniel J Leahy; Robert J Linhardt
Journal:  Biochemistry       Date:  2007-03-10       Impact factor: 3.162

Review 10.  The Hedgehog protein family.

Authors:  Thomas R Bürglin
Journal:  Genome Biol       Date:  2008-11-19       Impact factor: 13.583

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