Literature DB >> 16677959

In vivo 13C NMR spectroscopy and metabolic modeling in the brain: a practical perspective.

Pierre-Gilles Henry1, Gregor Adriany, Dinesh Deelchand, Rolf Gruetter, Malgorzata Marjanska, Gülin Oz, Elizabeth R Seaquist, Alexander Shestov, Kâmil Uğurbil.   

Abstract

In vivo 13C NMR spectroscopy has the unique capability to measure metabolic fluxes noninvasively in the brain. Quantitative measurements of metabolic fluxes require analysis of the 13C labeling time courses obtained experimentally with a metabolic model. The present work reviews the ingredients necessary for a dynamic metabolic modeling study, with particular emphasis on practical issues.

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Year:  2006        PMID: 16677959     DOI: 10.1016/j.mri.2006.01.003

Source DB:  PubMed          Journal:  Magn Reson Imaging        ISSN: 0730-725X            Impact factor:   2.546


  44 in total

1.  A two-compartment mathematical model of neuroglial metabolism using [1-(11)C] acetate.

Authors:  Bernard Lanz; Kai Uffmann; Matthias T Wyss; Bruno Weber; Alfred Buck; Rolf Gruetter
Journal:  J Cereb Blood Flow Metab       Date:  2011-11-30       Impact factor: 6.200

Review 2.  The micro-architecture of the cerebral cortex: functional neuroimaging models and metabolism.

Authors:  Jorge J Riera; Arne Schousboe; Helle S Waagepetersen; Clare Howarth; Fahmeed Hyder
Journal:  Neuroimage       Date:  2008-01-11       Impact factor: 6.556

Review 3.  Research applications of magnetic resonance spectroscopy to investigate psychiatric disorders.

Authors:  Stephen R Dager; Neva M Corrigan; Todd L Richards; Stefan Posse
Journal:  Top Magn Reson Imaging       Date:  2008-04

4.  Altered brain mitochondrial metabolism in healthy aging as assessed by in vivo magnetic resonance spectroscopy.

Authors:  Fawzi Boumezbeur; Graeme F Mason; Robin A de Graaf; Kevin L Behar; Gary W Cline; Gerald I Shulman; Douglas L Rothman; Kitt F Petersen
Journal:  J Cereb Blood Flow Metab       Date:  2009-09-30       Impact factor: 6.200

Review 5.  How and when the fMRI BOLD signal relates to underlying neural activity: the danger in dissociation.

Authors:  Arne Ekstrom
Journal:  Brain Res Rev       Date:  2009-12-21

6.  Quantitative assessment of brain glucose metabolic rates using in vivo deuterium magnetic resonance spectroscopy.

Authors:  Ming Lu; Xiao-Hong Zhu; Yi Zhang; Gheorghe Mateescu; Wei Chen
Journal:  J Cereb Blood Flow Metab       Date:  2017-05-15       Impact factor: 6.200

Review 7.  The use of hyperpolarized carbon-13 magnetic resonance for molecular imaging.

Authors:  Sarmad Siddiqui; Stephen Kadlecek; Mehrdad Pourfathi; Yi Xin; William Mannherz; Hooman Hamedani; Nicholas Drachman; Kai Ruppert; Justin Clapp; Rahim Rizi
Journal:  Adv Drug Deliv Rev       Date:  2016-09-04       Impact factor: 15.470

Review 8.  Imaging and spectroscopic approaches to probe brain energy metabolism dysregulation in neurodegenerative diseases.

Authors:  Gilles Bonvento; Julien Valette; Julien Flament; Fanny Mochel; Emmanuel Brouillet
Journal:  J Cereb Blood Flow Metab       Date:  2017-03-09       Impact factor: 6.200

9.  Determination of oxidative glucose metabolism in vivo in the young rat brain using localized direct-detected ¹³C NMR spectroscopy.

Authors:  Kathleen Ennis; Dinesh Kumar Deelchand; Ivan Tkac; Pierre-Gilles Henry; Raghavendra Rao
Journal:  Neurochem Res       Date:  2011-06-10       Impact factor: 3.996

Review 10.  New technologies - new insights into the pathogenesis of hepatic encephalopathy.

Authors:  Luisa Baker; Bernard Lanz; Fausto Andreola; Javier Ampuero; Anisha Wijeyesekera; Elaine Holmes; Nicolaas Deutz
Journal:  Metab Brain Dis       Date:  2016-09-30       Impact factor: 3.584

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