AIM: To evaluate periodontal disease (PD) influence on changes in high-sensitivity C-reactive protein (hsCRP) concentrations in patients with acute coronary syndromes and coexistent PD. MATERIALS AND METHODS: Dental examinations were carried out in a group of 50 consecutive patients, less than 60 years old, hospitalized as a result of acute coronary syndromes. The patients were divided into two groups on the basis of own-constructed combined PD score (group 2: more advanced; and group 1: less advanced PD) as well as clinical attachment loss (CAL) - group 4: CAL >3 mm; group 3: CAL <or=3 mm. Blood samples for hsCRP estimation were taken at admission, after 10/12 days and long term after acute coronary syndromes. RESULTS: A statistically significant decrease in hsCRP was observed among three consecutive blood sample examinations in groups 2 and 4, whereas it was only seen between examination 1 and examination 2 in groups 1 and 3. CONCLUSIONS: Although no statistically significant difference of hsCRP was found between studied groups, patients with less advanced PD, either estimated with the use of own-constructed combined score or on the basis of CAL, have significantly longer diminution of inflammatory response monitored with hsCRP concentrations.
AIM: To evaluate periodontal disease (PD) influence on changes in high-sensitivity C-reactive protein (hsCRP) concentrations in patients with acute coronary syndromes and coexistent PD. MATERIALS AND METHODS: Dental examinations were carried out in a group of 50 consecutive patients, less than 60 years old, hospitalized as a result of acute coronary syndromes. The patients were divided into two groups on the basis of own-constructed combined PD score (group 2: more advanced; and group 1: less advanced PD) as well as clinical attachment loss (CAL) - group 4: CAL >3 mm; group 3: CAL <or=3 mm. Blood samples for hsCRP estimation were taken at admission, after 10/12 days and long term after acute coronary syndromes. RESULTS: A statistically significant decrease in hsCRP was observed among three consecutive blood sample examinations in groups 2 and 4, whereas it was only seen between examination 1 and examination 2 in groups 1 and 3. CONCLUSIONS: Although no statistically significant difference of hsCRP was found between studied groups, patients with less advanced PD, either estimated with the use of own-constructed combined score or on the basis of CAL, have significantly longer diminution of inflammatory response monitored with hsCRP concentrations.
Authors: Maciej R Czerniuk; Zbigniew Bartoszewicz; Iwona Dudzik-Niewiadomska; Tomasz Pilecki; Renata Górska; Krzysztof J Filipiak Journal: Cardiol J Date: 2017-07-17 Impact factor: 2.737
Authors: Stanisław Surma; Monika Romańczyk; Justyna Witalińska-Łabuzek; Maciej R Czerniuk; Krzysztof Łabuzek; Krzysztof J Filipiak Journal: Curr Hypertens Rep Date: 2021-05-07 Impact factor: 5.369
Authors: Maciej R Czerniuk; Stanisław Surma; Monika Romańczyk; Jacek M Nowak; Andrzej Wojtowicz; Krzysztof J Filipiak Journal: Biology (Basel) Date: 2022-02-09
Authors: Bożena Szyguła-Jurkiewicz; Michał Zakliczyński; Michał Ploch; Mateusz Mościński; Robert Partyka; Romuald Wojnicz; Marian Zembala; Lech Poloński Journal: Kardiochir Torakochirurgia Pol Date: 2014-03-27